Search
Now showing items 1-10 of 50
A novel deep learning technique for morphology preserved fetal ECG extraction from mother ECG using 1D-CycleGAN
(
Elsevier
, 2024 , Article)
The non-invasive fetal electrocardiogram (fECG) enables easy detection of developing heart abnormalities, leading to a significant reduction in infant mortality rate and post-natal complications. Due to the overlapping of ...
Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study
(
Springer
, 2024 , Article)
Introduction: Alzheimer’s Disease (AD) is complex and novel approaches are urgently needed to aid in diagnosis. Blood is frequently used as a source for biomarkers; however, its complexity prevents proper detection. The ...
Impact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018
(
Taylor and Francis Ltd.
, 2024 , Article)
This study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio ...
Use of conditional estimates of effect in cancer epidemiology: An application to lung cancer treatment
(
Elsevier
, 2024 , Article)
Background: In oncology clinical trials, there is the assumption that randomization sufficiently balances confounding covariates and therefore average treatment effects are usually reported. This paper explores the wider ...
Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): A randomised controlled trial protocol
(
BMJ Publishing Group
, 2024 , Article)
Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion ...
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
(
Elsevier B.V.
, 2024 , Article)
The unfolded protein response (UPR) detects increased misfolded proteins and activates protein refolding, protein degradation and inflammatory responses. UPR sensors in the endoplasmic reticulum, IRE1α and PERK, bind and ...
Breast lump as the initial presentation of metastatic uterine leiomyosarcoma: a case report and comprehensive literature review
(
Medicinska Naklada Zagreb
, 2024 , Article)
Uterine leiomyosarcoma (uLMS) is a rare but aggressive cancer with a high metastatic potential and an unfavo-rable prognosis. A 54-year-old woman with a history of uterine fibroids clinically presented with a painless, ...
A Pilot Randomized Controlled Trial of De Novo Belatacept-based Immunosuppression After Lung Transplantation.
(
Wolters Kluwer Health
, 2024 , Article)
Chronic lung allograft dysfunction (CLAD) is the leading cause of death beyond the first year after lung transplantation. The development of donor-specific antibodies (DSA) is a recognized risk factor for CLAD. Based on ...
Determining the conclusiveness of a meta-analysis.
(
Wolters Kluwer Health
, 2024 , Article)
The pursuit of conclusive evidence related to an unanswered foreground (decision-making) question has been the driving factor behind multiple ongoing and planned randomized controlled trials as well as meta-analyses. ...
Comparison of bias adjustment in meta-analysis using data-based and opinion-based methods.
(
Wolters Kluwer Health
, 2024 , Article)
Several methods exist for bias adjustment of meta-analysis results, but there has been no comprehensive comparison with unadjusted methods. We compare 6 bias-adjustment methods with 2 unadjusted methods to examine how these ...