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Development of a biocompatible creatinine-based niosomal delivery system for enhanced oral bioavailability of clarithromycin
(
Taylor and Francis Ltd
, 2016 , Article)
Context: Nonionic surfactant vesicles have gained increasing scientific attention for hydrophobic drugs delivery due to their biocompatibility, stability and low cost. Objective: The aim of the present study was to synthesize ...
Epinephrine in anaphylaxis: Preclinical study of pharmacokinetics after sublingual administration of taste-masked tablets for potential pediatric use
(
MDPI AG
, 2018 , Article)
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to ...
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
(
Pakistan Journal of Pharmaceutical Sciences
, 2021 , Article)
Piroxicam (PC) is a non-steroidal anti-inflammatory drug characterized by poor aqueous solubility and
reported to cause and impart crucial GIT irritation, bleeding, peptic and duodenal ulcer. Engineering of PC ...
Prospects of Curcumin Nanoformulations in Cancer Management
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
There is increasing interest in the use of natural compounds with beneficial pharmacological effects for managing diseases. Curcumin (CUR) is a phytochemical that is reportedly effective against some cancers through its ...
Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve ...