Search
Now showing items 1-10 of 65
The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
(
MDPI AG
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals
(
Springer International Publishing
, 2014 , Article Review)
Management of HIV and malaria co-infection is challenging due to potential drug-drug interactions between antimalarial and HIV-antiviral drugs. Little is known of the clinical significance of these drug interactions, and ...
The Therapeutic Effects of Camel Milk: A Systematic Review of Animal and Human Trials
(
SAGE Publications Ltd
, 2016 , Article Review)
The clinical effectiveness and value of camel milk as a therapeutic agent is currently unclear. MEDLINE (1946 to March 2016), EMBASE (1974 to March 2016), and Google Scholar were searched using the following terms: milk, ...
AMP-activated protein kinase as a drug target in chronic kidney disease
(
Bentham Science Publishers B.V.
, 2018 , Article Review)
Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ...
Optimizing assessors’ mental workload in rater-based assessment: a critical narrative review
(
Bohn Stafleu van Loghum
, 2019 , Article Review)
Introduction
Rater-based assessment has resulted in high cognitive demands for assessors within the education of health professionals. Rating quality may be influenced by the mental workload required of assessors to ...
Is pyridoxine effective and safe for post-partum lactation inhibition? A systematic review
(
Blackwell Publishing Ltd
, 2017 , Article Review)
What is known and objective: It has been suggested that pyridoxine has an antilactogenic effect. Studies of the efficacy of pyridoxine in suppressing lactation have reported conflicting results. The aim of this review was ...
Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis
(
SAGE Publications Inc.
, 2017 , Article Review)
Objective: To summarize and evaluate the existing literature regarding medications to treat Parkinson's disease (PD) psychosis. Data Sources: MEDLINE (1946 to March 2017), EMBASE (1980 to March 2017), CINAHL (1982 to March ...
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
(
Frontiers Media
, 2019 , Article Review)
Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ...
A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies
(
Springer International Publishing
, 2017 , Article Review)
Meropenem is a carbapenem antibiotic that exhibits time-dependent bactericidal activity, traditionally dosed intravenously at 1�g every 8�h. In order to maximize its pharmacodynamic activity and reduce costs, an alternative ...
A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
(
SAGE Publications Inc.
, 2017 , Article Review)
Background/Objective: To improve antimicrobial utilization, development and implementation of antimicrobial stewardship programs in the emergency department (ED) has been recommended. The primary objective of this review ...