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Taxane anticancer formulations: challenges and achievements
(
Academic Press
, 2020 , Book chapter)
Taxanes represent a prominent anticancer family. Paclitaxel and docetaxel are the most well-known taxanes owing to their activity against many types of cancers. The poor solubility of taxanes in water is a major obstacle ...
Pharmacoeconomic Evaluations of Oral Anticancer Agents. Thematic Systematic Review
(
Hamad bin Khalifa University Press (HBKU Press)
, 2014 , Conference Paper)
Background: Around 14.1 million new cancer cases and 8.2 million deaths caused by cancer were reported in 2012, expected to rise up to 22 million within the next 2 decades. The parenteral route (intravenous dosage form) ...
Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model.
(
MDPI
, 2022 , Article)
Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ...
Soliciting the Oral Route as a Logical Approach to Managing Colon Cancer
(
Frontiers Media S.A.
, 2021 , Article)
According to Global Cancer Incidence, Mortality and Prevalence (GLOBOCAN) 2018, colon cancer (CC) is the third most common cancer in men and second in women worldwide (Bray et al., 2018). Approximately 1.8 million new colon ...
Preventive and Therapeutic Effects of Punica granatum (Pomegranate) in Respiratory and Digestive Diseases: A Review
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
The pomegranate fruit is made of white to deep purple seeds that are enclosed in a white, spongy, astringent membrane, also known as pericarp, covered by a thick red skin and a crown-shaped calyx. It contains a variety of ...
Editorial: Anti-cancer drug delivery: lipid-based nanoparticles
(
Frontiers Media SA
, 2023 , Other)
Cancer continues to pose significant challenges that require extensive attention and efforts from the scientific community. The battle against cancer encompasses the development of effective and safe therapeutic approaches. ...
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
(
Frontiers Media SA
, 2024 , Article)
In the current study, Neosetophomone B (NSP-B) was investigated for its anti-cancerous potential using network pharmacology, quantum polarized ligand docking, molecular simulation, and binding free energy calculation. Using ...