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Now showing items 171-180 of 542
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
The Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced Cardiotoxicity
(
OMICS International
, 2015 , Article)
Background: Doxorubicin (DOX), a widely used anticancer drug, has been associated with cardiotoxicity.
Recently, DOX-induced cardiotoxicity has been attributed to topoisomerase II (TOPII)-β expression and activity. In
our ...
Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
(
Mary Ann Liebert, Inc.
, 2017 , Article)
Aims: Circulating microparticles (MPs) from metabolic syndrome patients
and those generated from apoptotic T-cells induce endothelial
dysfunction; however, the molecular and cellular mechanism(s) underlying
in the effects ...
Assessment of utilization pattern of fixed dose drug combinations in primary, secondary and tertiary healthcare centers in Nepal: A cross-sectional study
(
BioMed Central Ltd.
, 2017 , Article)
Background: Prescription practices, especially in South Asian countries, have come under investigation for quality. Although there have been no studies in Nepal that have analyzed the prescription pattern of FDCs for ...
In Vivo Evaluation of Taste-Masked Fast-Disintegrating Sublingual Tablets of Epinephrine Microcrystals
(
Springer New York LLC
, 2018 , Article)
n community settings, IM injection of 0.3 mg epinephrine (Epi) using an auto-injector is the drug of choice for treatment of anaphylaxis. Previously, a taste-masking (TM) formulation of fast-disintegrating sublingual tablets ...
Spray-Dried Proliposome Microparticles for High-Performance Aerosol Delivery Using a Monodose Powder Inhaler
(
Springer New York LLC
, 2018 , Article)
© 2018, American Association of Pharmaceutical Scientists. Proliposome formulations containing salbutamol sulphate (SS) were developed using spray drying, and the effects of carrier type (lactose monohydrate (LMH) or ...
Pharmacogenomics In Pharmacy Practice: Current Perspectives.
(
Dove Medical Press
, 2019 , Article)
Pharmacogenomics (i.e., the application of genetic information in predicting an individual's response to drug therapy) plays an increasingly important role in drug development and decision-making regarding precision medicine. ...
Evaluation of an intensive education program on the treatment of tobacco-use disorder for pharmacists: A study protocol for a randomized controlled trial
(
BioMed Central Ltd.
, 2019 , Article)
Background: Tobacco use is presently responsible for the death of over seven million people across the world. In Qatar, it is one of the main causes of premature deaths and preventable diseases. To reduce tobacco use, Qatar ...
Smartphone use and acceptability amongst undergraduate pharmacy students
(
International Pharmaceutical Federation
, 2018 , Article)
Background: Smartphones offer unique resources useful for practicing pharmacists; however their acceptance among students within pharmacy educational institutions as learning tools remains unclear. Method: A 30-point ...
Arbutus andrachne L. Reverses Sleep Deprivation-Induced Memory Impairments in Rats
(
Humana Press Inc.
, 2018 , Article)
Sleep deprivation (SD) is associated with cognitive deficits. It was found to affect the hippocampus region of the brain by impairing memory formation. This impairment is suggested to be caused by elevation in oxidative ...