Browsing College of Health Sciences by Title
Now showing items 1482-1501 of 1584
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ... -
The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1
( Public Library of Science , 2020 , Article)The SARS-CoV-2 (COVID-19) pandemic is a global crisis that threatens our way of life. As of November 18, 2020, SARS-CoV-2 has claimed more than 1,342,709 lives, with a global mortality rate of ~2.4% and a recovery rate of ... -
Transforming cancer clinical trials: The integral role of artificial intelligence in electronic health records for efficient patient recruitment
( Elsevier , 2023 , Article)Healthcare is one of the sectors where artificial intelligence (AI) is currently viewed as a crucial driving factor. Patient care, medical research, and clinical trial enrollment could all significantly improve due to AI's ... -
Translation, Cross-Cultural Adaptation and Psychometric Validation of the Arabic Version of the Cardiac Rehabilitation Barriers Scale (CRBS-A) with Strategies to Mitigate Barriers
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Cardiac rehabilitation (CR) utilization is low, particularly in Arabic-speaking countries. This study aimed to translate and psychometrically validate the CR Barriers Scale in Arabic (CRBS-A), as well as strategies to ... -
Translation, Cross-Cultural Adaptation and Psychometric Validation of the Arabic Version of the Cardiac Rehabilitation Barriers Scale (CRBS-A) with Strategies to Mitigate Barriers
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Cardiac rehabilitation (CR) utilization is low, particularly in Arabic-speaking countries. This study aimed to translate and psychometrically validate the CR Barriers Scale in Arabic (CRBS-A), as well as strategies to ... -
Translation, cultural adaptation and validation of the Arabic version of the king’s Parkinson’s disease pain scale
( Taylor & Francis , 2023 , Article)Purpose: Pain in Parkinson’s disease (PD) is a highly prevalent non-motor symptom occurring in this population. The King’s PD Pain Scale (KPPS) was developed to assess pain in people with PD. This study aimed to provide a ... -
Traumatic brain injury: Oxidative stress and novel anti-oxidants such as mitoquinone and edaravone
( MDPI , 2020 , Article Review)Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually ... -
Treatment as prevention for hepatitis C virus in the Middle East and North Africa: a modeling study
( Frontiers Media SA , 2023 , Article)Background: Direct-acting antivirals opened an opportunity for eliminating hepatitis C virus (HCV) infection in the Middle East and North Africa (MENA), the region most affected by HCV infection. Impact of HCV treatment ... -
Trends and socioeconomic factors associated with overweight/obesity among three reproductive age groups of women in Nepal
( Wiley , 2021 , Article)Introduction: Overweight/obesity represents a major and increasing burden in Nepal where women in reproductive-aged groups are highly affected. We aimed to explore the trends and association of overweight by socioeconomic ... -
Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar
( Elsevier , 2022 , Article)Background Prevalence trends from Arabic speaking countries on psychiatric symptoms before and after the first wave of the COVID-19 pandemic are lacking. We estimated the point prevalence and change in depression and ... -
Trends in the burden and determinants of hypertensive heart disease in the Eastern Mediterranean region, 1990-2019: an analysis of the Global Burden of Disease Study 2019
( Elsevier , 2023 , Article)Background: Hypertensive heart disease (HHD), one of the end-organ damage consequences of hypertension, is an important public health issue worldwide. Data on the HHD burden in the Eastern Mediterranean region (EMR) are ... -
Trends of mortality attributable to child and maternal undernutrition, overweight/obesity and dietary risk factors of non-communicable diseases in sub-Saharan Africa, 1990-2015: Findings from the Global Burden of Disease Study 2015
( Cambridge University Press , 2019 , Article)Objective To assess trends of mortality attributable to child and maternal undernutrition (CMU), overweight/obesity and dietary risks of non-communicable diseases (NCD) in sub-Saharan Africa (SSA) using data from the ... -
Trilayer composite scaffold for urethral reconstruction: in vitro evaluation of mechanical, biological, and angiogenic properties
( IOP Publishing , 2024 , Article)Regeneration of damaged urethral tissue remains a major challenge in the field of lower urinary tract reconstruction. To address this issue, various synthetic and natural biodegradable biomaterials are currently being ... -
Tumor reversion: a dream or a reality.
( Pubmed , 2021 , Article)Reversion of tumor to a normal differentiated cell once considered a dream is now at the brink of becoming a reality. Different layers of molecules/events such as microRNAs, transcription factors, alternative RNA splicing, ... -
Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar
( BMJ Publishing Group , 2023 , Article)Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes. Methods ... -
Two patients with Canavan disease and structural modeling of a novel mutation.
( Springer US , 2017 , Article)Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme, which catalyzes the hydrolysis ... -
Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
( Elsevier , 2021 , Article)We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or ... -
Type 2 diabetes epidemic and key risk factors in Qatar: A mathematical modeling analysis
( BMJ Journal , 2022 , Article)Introduction We aimed to characterize and forecast type 2 diabetes mellitus (T2DM) disease burden between 2021 and 2050 in Qatar where 89% of the population comprises expatriates from over 150 countries. Research design ... -
Type 2 diabetes mellitus in pregnancy: The impact of maternal weight and early glycaemic control on outcomes.
( Elsevier , 2018 , Article)To study the pregnancy outcomes in women with type 2 diabetes mellitus (T2DM) and to relate these to maternal risk factors. We conducted a retrospective study of 419 women with T2DM (index group)- who attended our diabetes ... -
U-shaped association between dietary calcium density intake during adolescence and hypertension in adulthood-a 20-y longitudinal nationwide study in China
( Cambridge University Press , 2021 , Article)Background and Aims: We assessed longitudinal association between calcium intake during adolescence and hypertension in adulthood. Methods and Results: Longitudinal study data of 1611 participants from the China Health and ...