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The march of pluripotent stem cells in cardiovascular regenerative medicine.
(
BMC
, 2018 , Article Review)
Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and mortality. Heart failure remains a major contributor to this mortality. Despite major therapeutic advances over the past decades, a ...
Antihypertensive indigenous lebanese plants: Ethnopharmacology and a clinical trial
(
MDPI AG
, 2019 , Article)
Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study ...
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes.
(
MDPI
, 2019 , Article)
Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), ...
Inflammogenesis of Secondary Spinal Cord Injury
(
Frontiers Media
, 2016 , Article)
Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ...
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
(
Elsevier
, 2016 , Article)
Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ...
Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway.
(
MDPI
, 2019 , Article)
Despite pharmacotherapeutic advances, cardiovascular disease (CVD) remains the primary cause of global mortality. Alternative approaches, such as herbal medicine, continue to be sought to reduce this burden. is recognized ...
Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.
(
MDPI
, 2019 , Article)
Dietary intake of natural antioxidants is thought to impart protection against oxidative-associated cardiovascular diseases. Despite many in vivo studies and clinical trials, this issue has not been conclusively resolved. ...
Flavonoids in hypertension: a brief review of the underlying mechanisms.
(
Elsevier
, 2019 , Article)
Flavonoids are a diverse group of bioactive polyphenolic compounds abundant in dietary plants and herbs. Regular consumption of flavonoids exerts cardio-vasculoprotective effects and may reduce the onset or progression of ...
Potential Adverse Effects of Resveratrol: A Literature Review.
(
MDPI
, 2020 , Article Review)
Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive ...
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
(
Frontiers Media S.A.
, 2020 , Article)
Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing
prevalence. They remain the leading causes of morbidity and mortality worldwide. The use
of medicinal herbs continues to be an ...