College of Health Sciences
Collections in this community
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Biomedical Sciences [644 items ]
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Health Sciences-CAS (pre 2016) [139 items ]
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Human Nutrition [350 items ]
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Physical Therapy & Rehabilitation [66 items ]
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Public Health [382 items ]
Recent Submissions
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Exploring the natural products chemical space to abrogate the F3L-dsRNA interface of monkeypox virus to enhance the immune responses using molecular screening and free energy calculations
( Frontiers Media SA , 2023 , Article)Amid the ongoing monkeypox outbreak, there is an urgent need for the rapid development of effective therapeutic interventions capable of countering the immune evasion mechanisms employed by the monkeypox virus (MPXV). The ... -
Editorial: Food literacy and healthy diets in childhood and adolescence
( Frontiers Media SA , 2024 , Other)The global shift in food systems has made processed food, which is nutrient-poor and energy-dense, readily available and convenient for individuals across all age groups, with a particular focus on children. This phenomenon ... -
Uncommon presentation of complicated internal hernia through the appendices epiploicae ring of adhesion: a clinical case study
( Frontiers Media , 2024 , Article)Background: Internal hernias are infrequent, yet serious, medical conditions with potentially severe consequences. An internal hernia resulting from an Appendices epiploicae (AE) ring is an especially rare cause, with a ... -
Quality-of-life among women with breast cancer: application of the international classification of functioning, disability and health model
( Frontiers Media SA , 2024 , Article)Background: This study aimed to identify the factors that influence Breast Cancer (BC) women’s quality of life (QoL) based on the International Classification of Functioning, Disability and Health (ICF) framework. Method: ... -
"I am not the same as before": a mixed-methods study on depression in people with spinal injury in Qatar
( Frontiers Media SA , 2024 , Article)Incidence of spinal injury is high in the Middle East and North African region (MENA) due to the high incidence of road traffic crashes. A spinal injury may trigger mental health issues. Compared to the general population, ... -
An insight into the clinical learning environment of dental institutes: a study in the twin cities of Pakistan
( Pakistan Medical Association , 2024 , Article)Objective: To assess the perceptions of dental students regarding their clinical learning environment in an urban setting. Method: This descriptive, cross-sectional survey was conducted from March 2020 to May 2021 after ... -
Dietary Patterns and Hypothyroidism in U.S. Adult Population
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)The thyroid gland produces hormones that are essential for various body functions. Hypothyroidism is defined as insufficient thyroid hormone production. Several studies have found associations between specific micronutrients ... -
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with pronounced immunogenicity, exhibiting rapid proliferation and immune cell infiltration into the tumor microenvironment. TNBC’s heterogeneity poses ... -
An optimized CT-dense agent perfusion and micro-CT imaging protocol for chick embryo developmental stages.
( BMC , 2024 , Article)Compared to classical techniques of morphological analysis, micro-CT (μ-CT) has become an effective approach allowing rapid screening of morphological changes. In the present work, we aimed to provide an optimized micro-CT ... -
Trilayer composite scaffold for urethral reconstruction: in vitro evaluation of mechanical, biological, and angiogenic properties
( IOP Publishing , 2024 , Article)Regeneration of damaged urethral tissue remains a major challenge in the field of lower urinary tract reconstruction. To address this issue, various synthetic and natural biodegradable biomaterials are currently being ... -
In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
( Elsevier , 2024 , Article)Heart failure (HF) is a multifactorial, heterogeneous systemic disease that is considered one of the leading causes of death and morbidity worldwide. It is well-known that endothelial dysfunction (ED) plays an important ... -
The Association between Lifestyle Factors and COVID-19: Findings from Qatar Biobank.
( MDPI , 2024 , Article)Coronavirus Disease 2019 (COVID-19) manifestations range from mild to severe life-threatening symptoms, including death. COVID-19 susceptibility has been associated with various factors, but studies in Qatar are limited. ... -
In vitro and in vivo efficacy of a novel quinuclidinone derivative against breast cancer
( International Institute of Anticancer Research , 2014 , Other)Previously, our laboratory reported on novel quinuclidinone derivatives that cause cytotoxicity in human non-small lung carcinoma epithelial cells null for p53 (H1299). The current study aims to investigate the effect of ... -
Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives
( Springer Nature , 2014 , Other)Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous ... -
Glucose- and triglyceride-lowering dietary penta-O-galloyl-α-D-glucose reduces expression of PPARγ and C/EBPα, induces p21-Mediated G1 phase cell cycle arrest, and inhibits adipogenesis in 3T3-L1 preadipocytes
( Thieme , 2015 , Article)Plant polyphenols, such as hydrolysable tannins, are present in the human diet and known to exhibit anti-diabetic and anti-obesity activity. We previously reported that the representative hydrolysable tannin compound ... -
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
( Taylor & Francis , 2015 , Article)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ... -
Metformin increases 3-hydroxy medium chain fatty acids in patients with type 2 diabetes: a cross-sectional pharmacometabolomic study
( Frontiers Media SA , 2024 , Article)Background: Metformin is a drug with a long history of providing benefits in diabetes management and beyond. The mechanisms of action of metformin are complex, and continue to be actively debated and investigated. The aim ... -
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
( Elsevier , 2024 , Article)In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ... -
Correction to: Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance (Molecular Cancer, (2020), 19, 1, (57), 10.1186/s12943-020-01175-9)
( BMC , 2020 , Other)Following the publication of the original article [1], authors have noticed that one of the authors, Syed Shadab Raza, was missing in the Authors’ Contributions section. Please see below updated section. -
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
( Frontiers Media , 2024 , Article Review)Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ...