Browsing Biomedical Sciences by Type "Article Review"
Now showing items 41-60 of 94
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Human monkeypox virus in the shadow of the COVID-19 pandemic
( Elsevier , 2023 , Article Review)Background: The end of smallpox in 1980 and the subsequent stopping of vaccination against smallpox was followed by the emergence of monkeypox (mpox), a viral disease of animal origin, meaning that it is transmitted from ... -
Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
( IMR Press , 2022 , Article Review)Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ... -
Impact of the MIF -173G/C variant on cardiovascular disease risk: a meta-analysis of 9,047 participants
( Frontiers Media SA , 2024 , Article Review)Introduction: Many factors contribute to the risk of cardiovascular disease (CVD), an umbrella term for several different heart diseases, including inflammation. Macrophage migration inhibitory factor (MIF) is an important ... -
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: a novel therapeutic target in early endothelial dysfunction of metabolic disease
( Elsevier Ltd , 2019 , Article Review)Over the past three decades, our view of the endothelium rapidly evolved from a static lining of the blood vessels to a dynamic determinant and regulator of vascular tone and homeostasis. It is now widely accepted that ... -
Implications and theragnostic potentials of circular RNAs in rheumatic diseases
( Elsevier , 2023 , Article Review)Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has shown that aberrant expression of circRNAs can ... -
Inflammation and hypertension: Underlying mechanisms and emerging understandings
( wiley online library , 2023 , Article Review)Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ... -
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ... -
The Interplay Between Diet and the Epigenome in the Pathogenesis of Type-1 Diabetes
( Frontiers , 2021 , Article Review)The autoimmune disease, Type 1 Diabetes Mellitus (T1DM), results in the destruction of pancreatic β-cells, and the International Diabetes Federation reports that its incidence is increasing worldwide. T1DM is a complex ... -
Laboratory challenges in the diagnosis of hepatitis E virus.
( Microbiology Society , 2018 , Article Review)Hepatitis E virus (HEV) is an RNA virus that is an important cause of both acute and chronic hepatitis worldwide. To date, there are eight HEV genotypes that can infect mammals. HEV-1 and HEV-2 infect exclusively humans, ... -
Leprosy: Comprehensive insights into pathology, immunology, and cutting-edge treatment strategies, integrating nanoparticles and ethnomedicinal plants
( Frontiers Media , 2024 , Article Review)Mycobacterium leprae is the causative agent responsible for the chronic disease known as leprosy. This condition is characterized by dermal involvement, often leading to peripheral nerve damage, sensory-motor loss, and ... -
The march of pluripotent stem cells in cardiovascular regenerative medicine.
( BMC , 2018 , Article Review)Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and mortality. Heart failure remains a major contributor to this mortality. Despite major therapeutic advances over the past decades, a ... -
Markers associated with covid-19 susceptibility, resistance, and severity
( MDPI AG , 2021 , Article Review)In December 2019, the latest member of the coronavirus family, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, leading to the outbreak of an unusual viral pneumonia known as coronavirus ... -
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
( Blackwell Publishing Inc. , 2018 , Article Review)Introduction Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ... -
Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections
( MDPI , 2023 , Article Review)Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ... -
The Microbiota and Gut-Related Disorders: Insights from Animal Models
( MDPI , 2020 , Article Review)Over the past decade, the scientific committee has called for broadening our horizons in understanding host–microbe interactions and infectious disease progression. Owing to the fact that the human gut harbors trillions ... -
MicroRNAs in Cardiac Hypertrophy
( MDPI AG , 2019 , Article Review)Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress and pathological conditions. Cardiac remodeling could be ... -
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
( MDPI , 2020 , Article Review)Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ... -
Novel CD44-downstream signaling pathways mediating breast tumor invasion
( Ivyspring International Publisher , 2018 , Article Review)CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways, including ... -
Novel therapeutic strategies for spinal osteosarcomas
( Elsevier , 2020 , Article Review)At the dawn of the third millennium, cancer has become the bane of twenty-first century man, and remains a predominant public health burden, affecting welfare and life expectancy globally. Spinal osteogenic sarcoma, a ... -
Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
( Taylor and Francis Ltd. , 2023 , Article Review)Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer ...