Browsing Biomedical Sciences by Publication Date
Now showing items 21-40 of 631
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Prevalence of Virulence/Stress Genes in Campylobacter Jejuni from Chicken Meat Sold in Qatari Retail Outlets
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Camplobacter spp., and the presence of five virulence genes (htrB, cdtB, clpB, cadF and ciaB) was assessed in isolates. Forty eight ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
Helminth Infections Among Long-Term-Residents and Settled Immigrants in Qatar in the Decade from 2005 to 2014: Temporal Trends and Varying Prevalence Among Subjects from Different Regional Origins
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)We analysed the prevalence of helminth infection in a dataset of 31,008 records of subjects referred for stool examination at the Hamad Medical Corporation over the course of a decade (2005 to 2014, inclusive). Overall ... -
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
( SciTechnol , 2016 , Article)In the era of new Hepatitis C Virus (HCV) therapy, and the detection of extrahepatic HCV reservoirs such as peripheral blood mononuclear cells and platelets, it is important to understand the factors underlying resistance ... -
Enhanced Identification of Transcriptional Enhancers Provides Mechanistic Insights into Diseases.
( Cell Press , 2016 , Article)Enhancers are distal cis-regulatory DNA elements that increase the expression of target genes. Various experimental and computational approaches including chromatin signature profiling have been developed to predict enhancers ... -
Macrophage Infection by Mycobacteria
( OMICS International , 2016 , Article)Mycobacterium tuberculosis is the etiological agent of tuberculosis. It is a pathogen that continues to draw international concerns particularly due to the emergence of multi-drug resistance and to the difficulties ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( HBKU Press , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
Helminth infections among long-term residents and settled immigrants in Qatar in the decade from 2005 to 2014: temporal trends and varying prevalence among subjects from different regional origins
( BioMed Central , 2016 , Article)Background: Travel and migration from developing regions, where tropical diseases are common, to more developed industrialised nations can contribute to the introduction and subsequent spread of infections. With its rapidly ... -
Epidemiology of diabetic ketoacidosis in Arab patients with type 1 diabetes: a systematic review.
( Wiley , 2016 , Article)Diabetic ketoacidosis (DKA) is an acute and risky complication of type 1 diabetes. The aim of this study is to build the overall rate of DKA in Arab patients with type 1 diabetes in the 22 Arab nations. This is expected ... -
Substances Secreted by Starved Human Dermal Fibroblasts Enhancing the Wound Healing Process in Rat without Scar: A Potential Acellular System for Wound Healing
( Hamad Bin Khalifa University Press , 2016 , Conference Paper)Background Despite being a major cellular component of various engineered skin substituent, underlying mechanism of successful fibroblast transplantation in wound healing is not clear. Here we show that substances derived ... -
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
( Qscience. , 2016 , Conference Paper)Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ... -
Assessment of morphological changes due to oxidative stress: leukodepleted packed red blood cells stored in SAGM
( Canadian Society of Transfusion Medicine , 2016 , Conference Paper)Background: In blood bank, the storage procedures of packed red blood cell (pRBC) require some conditions to ensure the maximum storage time for a safe blood supply. pRBC can be stored up to 42 days in 2-6⁰C, as long as ... -
Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries.
( Current Medicine Group , 2016 , Article)Type 1 diabetes (T1D) is a complex autoimmune disorder that results from the T cell-mediated destruction of the pancreatic β cells and is due to interactions between environmental and genetic factors. Although Arabs have ... -
Novel mutation in an Egyptian patient with infantile Canavan disease.
( Springer Verlag (Germany) , 2016 , Article)Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme that catalyzes the deacetylation ... -
Structural modeling of p.V31F variant in the aspartoacylase gene.
( Springer Verlag , 2016 , Article)Aspartoacylase (ASPA) is an abundant enzyme in the brain, which catalyzes the conversion of N-acetylaspartate into acetate and aspartate, deficiency in its activity leads to degeneration of the white matter of the brain ... -
Prevalence of Virulence/Stress Genes in Campylobacter jejuni from Chicken Meat Sold in Qatari Retail Outlets
( Public Library of Science , 2016 , Article)Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Campylobacter spp. and the presence of five virulence genes (htrB, cdtB, clpP, cadF and ciaB) was assessed in isolates. Forty eight ... -
Accredited genetic testing in the Arab Gulf region: reinventing the wheel.
( Nature Publishing Group , 2016 , Article)Accredited genetic testing in the Arab Gulf region: reinventing the wheel. -
A decade of intestinal protozoan epidemiology among settled immigrants in Qatar
( PubMed Central , 2016 , Article)Background: The World Health Organization estimates that about 3.5 billion people worldwide are affected by intestinal parasitic infections. Reports have already emphasized the role of immigrants in outbreaks of ... -
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
( Impact Journals , 2016 , Article)Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ... -
Severe neurological manifestations in an Egyptian patient with a novel frameshift mutation in the Glutaryl-CoA dehydrogenase gene
( Springer US , 2016 , Article)Abstract To characterize an Egyptian patient with glutaric acidemia type I (GA I) and to identify the causative mutation( s) that may be responsible for the disease phenotype. MRI was performed on the patient using the ...