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Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
(
Frontiers Media
, 2023 , Article Review)
Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ...
Traumatic brain injury: Oxidative stress and novel anti-oxidants such as mitoquinone and edaravone
(
MDPI
, 2020 , Article Review)
Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually ...
Epac in vascular smooth muscle cells
(
MDPI
, 2020 , Article Review)
Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process ...
Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes
(
MDPI
, 2023 , Article Review)
The increasing popularity of electronic cigarettes (e-cigarettes) as an alternative to conventional tobacco products has raised concerns regarding their potential adverse effects. The cardiovascular system undergoes intricate ...
The Immunomodulatory Role of Microbiota in Rheumatic Heart Disease: What Do We Know and What Can We Learn from Other Rheumatic Diseases?
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article Review)
Rheumatic heart disease (RHD) represents a serious cardiac sequela of acute rheumatic fever, occurring in 30-45% of patients. RHD is multifactorial, with a strong familial predisposition and known environmental risk factors ...
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
(
MDPI
, 2023 , Article Review)
Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ...
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
(
MDPI
, 2024 , Article Review)
Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...
The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
(
Springer Science and Business Media B.V.
, 2023 , Article Review)
Background and Aim
The impact of multiple risk factors on COVID-19 mortality has been previously reported in multiple systematic reviews and meta-analyses. The aim of this review is to provide a comprehensive update on ...
Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives
(
Frontiers Media
, 2024 , Article Review)
Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ...
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article Review)
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with pronounced immunogenicity, exhibiting rapid proliferation and immune cell infiltration into the tumor microenvironment. TNBC’s heterogeneity poses ...