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Support of intelligent emergent materials to combat COVID-19 pandemic
(
Springer
, 2021 , Article)
The COVID-19 pandemic, associated with SARS-CoV-2 infection
transmitted via human to human and cause lifethreatening
respiratory diseases, has emerged as an everincreasing
global health and economic crisis since its ...
Microfluidic-based virus detection methods for respiratory diseases
(
Springer
, 2021 , Article)
With the recent SARS-CoV-2 outbreak, the importance of rapid and direct detection of respiratory disease viruses has been well recognized. The detection of these viruses with novel technologies is vital in timely prevention ...
Comparing Levels of Metabolic Predictors of Coronary Heart Disease between Healthy Lean and Overweight Females.
(
MDPI
, 2021 , Article)
Screening for the metabolomic signature of coronary heart disease (CHD) before disease onset could help in early diagnosis and potentially disease prevention. In this study, the levels of 17 CHD metabolic biomarkers in ...
Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
(
American Physiological Society
, 2021 , Article)
Many patients who suffer from pulmonary diseases cannot inflate their lungs normally, as they need mechanical ventilation (MV) to assist them. The stress associated with MV can damage the delicate epithelium in small airways ...
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.
(
Nature Research
, 2021 , Article)
The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. ...
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
(
MDPI
, 2021 , Article)
The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ...
Computational Investigation of the Effect of Wall Thickness on Rupture Risk in Abdominal Aortic Aneurysms
(
JAFM
, 2020 , Article)
Cardiovascular disorders are among the most important causes of sudden death and adult disability worldwide. Abdominal aortic aneurysm (AAA) is a critical clinical condition where the aorta dilates beyond 50% of its normal ...
Salmonella Infections among Pediatric Population in Qatar: Phenotypic Resistance and Associated Genotypic Determinants
(
Austin Publishing Group
, 2021 , Article)
Salmonella is a significant public health burden worldwide and being the
most common bacterial diarrheal illness among infants and young children. In
the last few years, Qatar reports a high incidence of salmonellosis ...
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery - A Follow-Up Study
(
Dovepress
, 2021 , Article)
Obesity is a chronic disorder characterized by a low-grade inflammatory state and immune cell irregularities. The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory ...
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
(
Elsevier
, 2021 , Article)
HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ...