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Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential.
(
Nature Publishing Group
, 2017 , Article)
The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ...
Nanotubes Impregnated Human Olfactory Bulb Neural Stem Cells Promote Neuronal Differentiation in Trimethyltin-induced Neurodegeneration Rat Model
(
Wiley
, 2017 , Article)
Neural stem cells (NSCs) are multipotent self-renewing cells that could be used in cellular-based therapy for a wide variety of neurodegenerative diseases including Alzheimer's diseases (AD), Parkinson's disease (PD), ...
Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats.
(
Nature Publishing Group
, 2016 , Article)
STUDY DESIGN:
Adult human olfactory bulb neural stem cells (OBNSCs) were isolated from human patients undergoing craniotomy for tumor resection. They were genetically engineered to overexpresses green fluorescent protein ...
Potential of Stem Cell-Based Therapy for Ischemic Stroke.
(
Frontiers Media
, 2018 , Article Review)
Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several studies have been devoted to assessing the ...