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Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.
(
Frontiers Media
, 2020 , Article)
The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ...
Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
(
Frontiers Media
, 2020 , Article)
© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ...
Metabolomics and doping analysis: promises and pitfalls.
(
Future Science
, 2020 , Article)
This brief commentary presents an overview of the potential utility of metabolomics-based approaches in doping
analysis, with particular emphasis on areas where the current analytical procedures would most benefit from ...
Metabolic profiling of elite athletes with different cardiovascular demand
(
John Wiley & Sons Ltd
, 2019 , Article)
Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ...
Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes
(
MDPI
, 2021 , Article Review)
Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere ...
High Endurance Elite Athletes Show Age-dependent Lower Levels of Circulating Complements Compared to Low/Moderate Endurance Elite Athletes
(
Frontiers Media
, 2021 , Article)
Introduction: Aerobic exercise activates the complement system in the peripheral blood. However, the effect of age and high intensity endurance training on the levels of circulating complements and sassociated inflammatory ...
Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
(
Frontiers Media
, 2021 , Article)
Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim ...
Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells
(
Frontiers Media
, 2022 , Article)
Introduction: The immunomodulatory effect of physical activity can impact insulin signaling differentially in adipose tissues and skeletal muscle cells, depending on sport intensity. In this study, the effect of serum from ...
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
(
Nature Research
, 2019 , Article)
Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ...