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Association of genes with phenotype in autism spectrum disorder.
(
Impact Journals
, 2019 , Article Review)
Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ...
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance.
(
Springer Verlag
, 2019 , Article)
The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor ...
Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk.
(
Frontiers Media
, 2019 , Article)
The ability of epithelial cells to organize through cell-cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions ...
Changes in resting-state functional brain activity are associated with waning cognitive functions in HIV-infected children.
(
Elsevier
, 2018 , Article)
Delayed brain development in perinatally HIV-infected children may affect the functional brain activity and subsequently cognitive function. The current study evaluated the functional brain activity in HIV-infected children ...
Brain Microstructural Changes Support Cognitive Deficits in Normal Children Born to HIVinfected Mothers
(2018 , Conference Proceedings)
Synopsis
In the current study, we evaluated the brain integrity [by mapping the fractional anisotropy (FA) and mean diffusivity (MD)] and neurocognitive
performance (NP) in normal children (NCI) born to HIV-infected ...
Single-Voxel H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD ) in humans at 7T using a 32-channel volume coil.
(
Wiley
, 2019 , Article)
Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD ) concentration may provide insights on its roles in normal and pathological aging. In the present study, we report a H MRS pulse sequence for the in ...
RAS-mediated oncogenic signaling pathways in human malignancies
(
Elsevier
, 2018 , Article Review)
Abnormally activated RAS proteins are the main oncogenic driver that governs the functioning of major signaling
pathways involved in the initiation and development of human malignancies. Mutations in RAS genes and
or its ...
Role of animal research in human malignancies
(
Elsevier
, 2019 , Book chapter)
Animal models are the central backbone in relation to providing the safety information of xenobiotics, the nature of chemicals present in the environment, and understanding the developmental process in disease pathogenesis ...