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Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties
(
Frontiers Media
, 2022 , Article)
Background: Breast cancer (BC) is the second most common cancer overall. In women, BC is the most prevalent cancer and the leading cause of cancer-related mortality. Triple-negative BC (TNBC) is the most aggressive BC, ...
Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar
(
MDPI
, 2019 , Article)
The present study is designed to compare demographic characteristics, plasma biochemistry, and the oral microbiome in obese (N = 37) and lean control (N = 36) subjects enrolled at Qatar Biobank, Qatar. Plasma hormones, ...
NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs
(
Walter de Gruyter
, 2022 , Article)
Systemic sclerosis (SSc) is an immune disorder characterized by diffuse fibrosis and vascular abnormalities of the affected organs. Although the etiopathology of this disease is largely unknown, endothelial damage and ...
Sestrin2 as a Protective Shield against Cardiovascular Disease
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
A timely and adequate response to stress is inherently present in each cell and is important for maintaining the proper functioning of the cell in changing intracellular and extracellular environments. Disruptions in the ...
Ameliorative role of dietary activated carbon against ochratoxin-A induced oxidative damage, suppressed performance and toxicological effects
(
Taylor and Francis Ltd.
, 2022 , Article)
The present study reports that dietary addition of 2.5, 5.0, 10.0 g/kg activated charcoal (AC) in broiler feed contaminated with 0.15, 0.3 and 1.0 mg/kg ochratoxin A (OTA) showed a partial reduction in intensity of mycotoxins ...
Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats
(
Frontiers Media S.A.
, 2022 , Article)
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum ...
Editorial: Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)
(
Frontiers Media S.A.
, 2022 , Other)
Cardiovascular disease is the leading cause of death worldwide, and diabetes, the most common metabolic syndrome, causes a 2–5 times higher risk for heart disease (1). Specifically, cardiovascular complications in people ...
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer cells
(
Frontiers Media
, 2024 , Article)
Natural products have long been utilized in traditional medicine as remedies to improve health and treat illnesses, and have had a key role in modern drug discovery. Recently, there has been a revived interest in the search ...
Corrigendum: Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats (Frontiers in Pharmacology, (2023), 14, (1305816), 10.3389/fphar.2023.1305816)
(
Frontiers Media SA
, 2024 , Other)
In the published article, there was an error in Figure 4A as published. During the last stage of revision, labels in Figure 4A were inadvertently altered, and the group labels in the figure were mistakenly substituted. The ...
Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats
(
Frontiers Media SA
, 2023 , Article)
Introduction: Oxidative stress is a major instigator of various cardiovascular diseases, including myocardial infarction (MI). Despite available drugs, there is still an increased need to look for alternative therapies or ...