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Now showing items 11-20 of 34
Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM
(
IntechOpen
, 2019 , Book chapter)
Obesity has become a global health issue due to its high prevalence and associated comorbidities including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Obesity is associated with the expansion of adipose ...
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
(
Frontiers Media S.A.
, 2020 , Article)
Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing
prevalence. They remain the leading causes of morbidity and mortality worldwide. The use
of medicinal herbs continues to be an ...
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
(
Elsevier
, 2021 , Article)
Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ...
Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a Lifetime.
(
Frontiers Media
, 2021 , Article)
Exercise training is one of the few therapeutic interventions that improves health span by delaying the onset of age-related diseases and preventing early death. The length of telomeres, the 5'-TTAGGG -3' tandem repeats ...
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
(
IMR Press
, 2022 , Article Review)
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ...
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
(
Elsevier Inc.
, 2016 , Article Review)
Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ...
BIAN N-heterocyclic gold carbene complexes induced cytotoxicity in human cancer cells via upregulating oxidative stress
(
Asian Pacific Organization for Cancer Prevention
, 2015 , Article)
Background: Nanoparticles of gold and silver are offering revolutionary changes in the field of cancer therapy. N-heterocyclic carbene (NHC) metal complexes possess diverse biological activities and are being investigated ...
Differences in platelet-rich plasma composition influence bone healing
(
John Wiley and Sons Inc
, 2021 , Article)
Aim: Platelet-rich plasma (PRP) is an autologous blood-derived material that has been used to enhance bone regeneration. Clinical studies, however, reported inconsistent outcomes. This study aimed to assess the effect of ...
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
(
Frontiers Media S.A.
, 2021 , Article)
Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. It ...
Chromium toxicity in plants: consequences on growth, chromosomal behavior and mineral nutrient status
(
the Scientific and Technological Research Council of Turkey (TUBITAK)
, 2022 , Article)
Chromium (Cr) is a heavy metal of commercial importance; thus, significant amounts are released in wastewaters. The mobility and distribution of metals in the environment is related not only to their concentration but also ...