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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background: Chronic kidney disease (CKD) is characterized by progressive decline in renal function; if left untreated, it ultimately results in end-stage renal disease (ESRD), a condition that demands either dialysis or ...
Comparison Of In Vitro Models Of Diabetic Nephropathy Using Renal Tubular Cells
(
Hamad bin Khalifa University Press (HBKU Press)
, 2014 , Conference Paper)
Background: Diabetic nephropathy (DN) is a chronic and serious complication associated with diabetes. The standardization of an in vitro model to best represent DN is very challenging due to the chronic nature of the ...
Synthesis And Pharmacological Screening Of Novel Piperine Analogs For Potential In Vitro Protection From Endoplasmic Reticulum Stress
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background: The endoplasmic reticulum (ER) is the chief organelle involved in protein homeostasis. Perturbations to the ER protein folding machinery caused by hyperlipidemia, hyperglycemia or hypoglycemia has been shown ...
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ...