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Cysteamine revisited: repair of arginine to cysteine mutations.
(
Springer Verlag
, 2017 , Article)
Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ...
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
(
Elsevier
, 2017 , Article)
Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ...
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
(
Elsevier
, 2017 , Other)
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ...
A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
(
Mary Ann Liebert
, 2017 , Article)
This declaration, signed by an interdisciplinary task force of 234 experts from 83 different countries with different backgrounds, highlights the threat posed by antimicrobial resistance and the need for appropriate use ...
Drug release kinetics from a drug-eluting stent with asymmetrical coat
(
IMR Press Limited
, 2017 , Article)
The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ...
Molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children
(
Frontiers Media S.A.
, 2017 , Article)
Pediatric diarrhea is a common cause of death among children under 5 years of age. In the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. Parasitic ...