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Now showing items 11-20 of 310
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
(
American Society for Biochemistry and Molecular Biology
, 2015 , Article)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...
Unique associations of the Job Demand-Control-Support model subscales with leisure-time physical activity and dietary energy intake
(
National Institute of Occupational Safety and Health
, 2018 , Article)
Leisure-time physical activity (LTPA) and dietary energy intake are two important health behaviours, which at too low or high levels respectively, are associated with overweight and obesity. This study explores associations ...
Production and Determination of Bioavailable Iron in Sorghum and White bean Noodles
(
Enviro Research
, 2014 , Article)
The objective of this study was to find innovative approaches for the production of iron
fortified noodles that are natural and economically feasible. The functional food was produced
using different combinations . The ...
Initial psychometric testing and validation of the Patient Participation in Pressure Injury Prevention scale
(
Wiley
, 2017 , Article)
AIMS:
The aim of this study was to develop the Patient Participation in Pressure Injury Prevention (PPPIP) scale and undertake initial testing of some of its psychometric properties.
BACKGROUND:
Clinical practice ...
Pharmacotherapy of Persons with Dementia in Long-Term Care in Australia: A Descriptive Audit of Central Nervous System Medications
(
Bentham Science Publishers
, 2017 , Article)
BACKGROUND:
Neuropsychiatric symptoms of dementia are often treated through the prescription of one or more psychotropic medications. However, limited efficacy and potential harmful side-effects has resulted in efforts ...
Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
(
Elsevier
, 2017 , Article)
Green tea consumption has been shown to possess cancer chemopreventive activity. Polyphenol E (PE) is a widely used standardized green tea extract formulation. This study was designed to investigate the impact of PE on ...
Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
(
Elsevier
, 2017 , Article)
Abstract We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell-penetrating peptide, the short ...
Bioavailability and hypolipidemic effects of peanut skin polyphenols
(
Mary Ann Liebert, Inc.
, 2015 , Article)
Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly
consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type ...
Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar.
(
Elsevier
, 2018 , Article)
Clinical Exome Sequencing (CES) has increasingly become a popular diagnostic tool in patients suffering from genetic disorders that are clinically and genetically complicated. Myeloproliferative Neoplasms (MPNs) is an ...
Resting Energy Expenditure in a Controlled Group of Young Arab Females: Correlations with Body Composition and Agreement with Prediction Equations
(
Scientific Research Publishing
, 2013 , Article)
Objectives: To assess correlates of body compositions measures and resting energy expenditure (REE) in young Arab females, and to compare measured REE values with values calculated from REE predictive equations. Methods: ...