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Now showing items 31-40 of 43
Prevention of oral cancer
(
Springer International Publishing
, 2017 , Book chapter)
Oral cancer has become a major debilitating incidence in both genders alike. Oral cancer, a part of head and neck cancer, is a combination of two types of cancer: oral cavity cancer and oropharyngeal cancer. The most common ...
Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope
(
Elsevier (Cell Press)
, 2017 , Article)
The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies ...
Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
(
Hindawi Publishing Corporation
, 2017 , Article)
Alterations in global DNA methylation are implicated in various pathophysiological processes. The development of simple and quick, yet robust, methods to assess DNA methylation is required to facilitate its measurement and ...
Novel Quinuclidinone Derivatives Induced Apoptosis in Human Breast Cancer via Targeting P53
(
Elsevier
, 2017 , Article)
Small molecules that can target human cancers have been highly sought to increase the anticancer efficacy, the present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). ...
Prevalence and molecular profiling of Epstein Barr virus (EBV) among healthy blood donors from different nationalities in Qatar.
(
Public Library of Science
, 2017 , Article)
The Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis. EBV is highly prevalent lymphotropic herpesvirus and has been linked to several malignancies. Transmission is generally by oral secretions, ...
Estimating Seroprevalence of Herpes Simplex Virus Type 1 among Different Middle East and North African Male Populations Residing in Qatar
(
Wiley
, 2017 , Article)
HSV-1 epidemiology in the Middle East and North Africa (MENA) remains poorly understood. Our study aimed to measure HSV-1 antibody prevalence (seroprevalence) and its age-distribution among select MENA populations residing ...
First study in Qatar to reveal high Legionella counts in cooling towers.
(
World Health Organization (WHO)
, 2017 , Other)
Legionella spp. is transmitted from water to humans by aerosol-generating devices, including cooling
towers (CTs). There have not been published reports about Legionella in these systems in Qatar. Ten CTs in Qatar
University ...
Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants.
(
Oxford University Press (OUP)
, 2017 , Article)
Isovaleric acidaemia (IVA) is an autosomal recessive inborn error of leucine metabolism. It is caused by a deficiency in the mitochondrial isovaleryl-CoA dehydrogenase (IVD) enzyme. In this study, we investigated eight ...
Cysteamine revisited: repair of arginine to cysteine mutations.
(
Springer Verlag
, 2017 , Article)
Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ...
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
(
Elsevier
, 2017 , Other)
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ...