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Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
(
Frontiers Media
, 2021 , Article)
The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ...
Do changes in ace-2 expression affect sars-cov-2 virulence and related complications: A closer look into membrane-bound and soluble forms
(
MDPI
, 2021 , Article Review)
The SARS-CoV-2 virus utilizes angiotensin converting enzyme (ACE-2) for cell entry and infection. This enzyme has important functions in the renin-angiotensin aldosterone system to preserve cardiovascular function. In ...
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
COVID-19 VACCINATION KNOWLEDGE AND HESITANCY AMONG STUDENTS AND EMPLOYEES AT QATAR UNIVERSITY; A CROSS-SECTIONAL STUDY
(2021 , Professional Masters Project)
Introduction: Vaccines are the most important and cost-effective public health tools known to control and prevent many infectious diseases. However, concerns regarding the safety and the need for a vaccine and reluctance ...
Antibiotics Prescribing in Intensive Care Settings during the COVID-19 Era: A Systematic Review
(
MDPI
, 2021 , Article)
The prevalence of patients admitted to intensive care units (ICUs) with SARS-CoV-2
infection who were prescribed antibiotics is undetermined and might contribute to the increased
global antibiotic resistance. This ...
Thrombotic and Hypercoagulability Complications of COVID-19: An Update
(
Dovepress
, 2021 , Article)
The current COVID-19 pandemic emerged in December 2019, in China, affecting millions of people worldwide. COVID-19 is mainly a disease of the respiratory system, yet systematic complications have also been reported among ...
Equity in vaccine trials for higher weight people ? Protocol for a rapid review of inclusion and exclusion criteria for higher weight people in clinical trials for COVID-19
(
BMJ Publishing Group
, 2021 , Article)
Introduction Vaccination is a public health strategy that aims to reduce the burden of viral illness, especially
important for populations known or likely to be at increased risk for inequitable outcomes due to the ...
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
(
Frontiers Media
, 2021 , Article)
Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...
Nutrition Management in COVID-19 Quarantine: Hospital-Based Study
(
Cambridge University Press
, 2021 , Article)
Background:
This hospital-based study aimed to evaluate the nutritional status and dietary habits for COVID-19 patients, the amount of nutrients provided to the patients in the hospital and to detect the predictors of ...