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The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals.
(
MDPI
, 2023 , Article)
Healthy non-obese insulin resistant (IR) individuals are at higher risk of metabolic syndrome. The metabolic signature of the increased risk was previously determined. Physical activity can lower the risk of insulin ...
Statistical methods and resources for biomarker discovery using metabolomics.
(
BMC
, 2023 , Article Review)
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and disease. Metabolic profiles provide a close insight into physiological states and are highly volatile to genetic and environmental ...
Exercise Metabolome: Insights for Health and Performance
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Exercise has many benefits for physical and mental well-being. Metabolomics research has allowed scientists to study the impact of exercise on the body by analyzing metabolites released by tissues such as skeletal muscle, ...
Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid
(
American Chemical Society (ACS)
, 2023 , Article)
Currently, permanent vascular stents are fabricated using titanium and stainless steel implants that are nondegradable and offer high stability, but they have certain disadvantages. For example, the prolonged exposition ...
The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
(
Frontiers Media
, 2023 , Article)
Background: The cross-protective nature of Bacillus Calmette-Guerin (BCG) vaccine against SARS-CoV-2 virus was previously suggested, however its effect in COVID-19 patients with type 2 diabetes (T2D) and the underlying ...
Molecular regulators of exercise-mediated insulin sensitivity in non-obese individuals
(
John Wiley and Sons Inc
, 2023 , Article)
Insulin resistance is a significant contributor to the development of type 2 diabetes (T2D) and is associated with obesity, physical inactivity, and low maximal oxygen uptake. While intense and prolonged exercise may have ...
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
(
MDPI
, 2023 , Article)
Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ...
The Relationship between Changes in MYBPC3 Single-Nucleotide Polymorphism-Associated Metabolites and Elite Athletes’ Adaptive Cardiac Function
(
MDPI
, 2023 , Article Review)
Athletic performance is a multifactorial trait influenced by a complex interaction of environmental and genetic factors. Over the last decades, understanding and improving elite athletes’ endurance and performance has ...
Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
(
Dove Medical Press
, 2023 , Article)
Introduction: Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress ...