Browsing Faculty Contributions by Author "Elrayess, Mohamed A."
Now showing items 1-20 of 34
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Amniotic stem cells as a source of regenerative medicine to treat female infertility
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Elrayess, Mohamed A.; Albanese, Chris ( Springer , 2022 , Article Review)Impaired reproductive health is a worldwide problem that affects the psychological well-being of a society. Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. ... -
Antioxidative Stress Metabolic Pathways in Moderately Active Individuals
Almuraikhy, Shamma; Anwardeen, Najeha; Doudin, Asmma; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2023 , Article)Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood. ... -
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
Thanassoulas, Angelos; Theodoridou, Maria; Barrak, Laila; Riguene, Emna; Alyaarabi, Tamader; Elrayess, Mohamed A.; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( MDPI , 2023 , Article)Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ... -
Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
Sohail, Muhammad U.; Al-Mansoori, Layla; Al-Jaber, Hend; Georgakopoulos, Costas; Donati, Francesco; Botrè, Francesco; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ... -
Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels
Amneh H., Tarkhan; Anwardeen, Najeha R.; Sellami, Maha; Donati, Francesco; Botrè, Francesco; de la Torre, Xavier; Elrayess, Mohamed A.... more authors ... less authors ( Elsevier , 2022 , Article)Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports participation, findings ... -
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
AlMuraikhy, Shamma; Anwardeen, Najeha; Naeem, Aisha; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Elrayess, Mohamed A... more authors ... less authors ( MDPI , 2022 , Article)(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy ... -
A comparison of isolation and culture protocols for human amniotic mesenchymal stem cells.
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Khan, Muhammad Jawad; Elrayess, Mohamed A; Cui, Wanxing; Albanese, Chris... more authors ... less authors ( Taylor and Francis , 2022 , Article Review)The successful translation of mesenchymal stem cells (MSCs) from bench to bedside is predicated upon their regenerative capabilities and immunomodulatory potential. Many challenges still exist in making MSCs a viable and ... -
Editorial: OMICS-based approaches in sports research volume II.
Elrayess, Mohamed A; Botrè, Francesco; Palermo, Amelia ( Frontiers Media , 2022 , Other)OMICS approaches, including genomics, epigenomics, transcriptomics, proteomics, and metabolomics, continue to provide invaluable tools for better understanding of the molecular mechanisms underlying various physiological ... -
Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells
Alheidous, Sara; Al-Muraikhy, Shamma; Rizk, Nasser; Sellami, Maha; Donati, Francesco; Botre, Francesco; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2022 , Article)Introduction: The immunomodulatory effect of physical activity can impact insulin signaling differentially in adipose tissues and skeletal muscle cells, depending on sport intensity. In this study, the effect of serum from ... -
Empower Generations: Longitudinal Study for National Capacities in Life Sciences and Healthcare
Althani, Asmaa Ali J.F.; Abu-El-Ruz, Rasha; Kurdi, Rana Mahmoud; Almeer, Naiema Hashem M.A.; Al-Ajli, Farooq Omar Maan; Al-Shafai, Mashael; Elgamal, Abdelrahman Mohamed; Latrous, Mariem Sirine; Hadwan, Tameem Ali Qaid; Abunada, Taghreed H.A.; Jamal, Zeina; Masoud, Ovelia Anan M.J.; Awada, Sawsan; Alkubaisi, Manal Rashid G.A.; Ibrahim, Amal Abdulsalam; Alhathal, Mishael Khalid M.; Alrumaihi, Shahd Khalifa S.R.; Boussalia, Souheila; Milan, Nancy; Bushra, Sumbul; Pakari, Jaafar Naser; Bishawi, Abdel Hakim; Elrayess, Mohamed A.; Alhussain, Hashim Abdelrahman Abdalla; Said, Sawsan S.A.; Salih, Reem Omar Mohamed... more authors ... less authors (2021 , Article)Background: The decrease in the number of adolescents showing genuine interest in the fields of healthcare has been one of the recent concerns worldwide. A plethora of studies have discussed the factors that influence ... -
Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid
Radwan, A. Bahgat; Okonkwo, Paul C.; Murugan, Srinivasan; Parande, Gururaj; Taryba, Maryna; Montemor, M. Fatima; Al-Mansoori, Layla; Elrayess, Mohamed A.; Al-Qahtani, Noora; Gupta, Manoj; Youssef, Khaled M.; Case, Raymundo; Shakoor, R. A.; Abdullah, Aboubakr M.... more authors ... less authors ( American Chemical Society (ACS) , 2023 , Article)Currently, permanent vascular stents are fabricated using titanium and stainless steel implants that are nondegradable and offer high stability, but they have certain disadvantages. For example, the prolonged exposition ... -
From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance.
Alser, Maha; Elrayess, Mohamed A ( MDPI , 2022 , Article Review)Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical studies, however, have described a ... -
Identification of Prognostic Metabolomic Biomarkers at the Interface of Mortality and Morbidity in Pre-Existing TB Cases Infected With SARS-CoV-2
Diboun, I.; Diboun, Ilhame; Cyprian, Farhan S.; Anwardeen, Najeha Rizwana; Yassine, Hadi M.; Elrayess, Mohamed A.; Rahmoon, Samreen Mumtaz; Sayed, Sarah Khaled; Schuchardt, Sven; Khatib, Malkan; Bansal, Devendra; Farag, Elmoubashar Abu Baker Abd; Emara, Mohamed M.; Abdallah, Abdallah M.... more authors ... less authors ( Frontiers Media S.A. , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection currently remains one of the biggest global challenges that can lead to acute respiratory distress syndrome (CARDS) in severe cases. In line with this, ... -
Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity
Almuraikhy, Shamma; Sellami, Maha; Al-Amri, Hadaia Saleh; Domling, Alexander; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( Dove Medical Press , 2023 , Article)Introduction: Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress ... -
Impact of phospholipids, surfactants and cholesterol selection on the performance of transfersomes vesicles using medical nebulizers for pulmonary drug delivery
Iftikhar, Khan; Needham, Rachel; Yousaf, Sakib; Houacine, Chahinez; Islam, Yamir; Bnyan, Ruba; Sadozai, Sajid Khan; Elrayess, Mohamed A.; Elhissi, Abdelbary... more authors ... less authors ( Elsevier , 2021 , Article)The aim of this study is to formulate and optimize novel transfersome formulations for pulmonary drug delivery. Transfersome formulations (F1 – F18) were prepared by a thin-film method using three phospholipids (Soya ... -
In Vitro and In Vivo Validation of GATA-3 Suppression for Induction of Adipogenesis and Improving Insulin Sensitivity
Al-Jaber, Hend; Mohamed, Nura A.; Govindharajan, Vijay K.; Taha, Samir; John, Jomon; Halim, Sharique; Alser, Maha; Al-Muraikhy, Shamma; Anwardeen, Najeha Rizwana; Agouni, Abdelali; Elhissi, Abdelbary; Al-Naemi, Hamda A.; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2022 , Article)Impaired adipogenesis is associated with the development of insulin resistance and an increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin ... -
Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization
Nada, Khudair; Agouni, Abdelali; Elrayess, Mohamed A.; Najlah, Mohammad; Younes, Husam M.; Elhissi, Abdelbary... more authors ... less authors ( Elsevier , 2020 , Article)Slurry-based Letrozole (LTZ)-loaded proniosomes were designed using sucrose or sorbitol as carriers and various ratios of cholesterol (CH) and Tween 80 (T80) as lipid composition. Proniosomes were hydrated and probe-sonicated ... -
Level of Maternal Respiratory Syncytial Virus (RSV) F Antibodies in Hospitalized Children and Correlates of Protection.
Taleb, Sara A; Al-Ansari, Khalid; Nasrallah, Gheyath K; Elrayess, Mohamed A; Al-Thani, Asmaa A; Derrien-Colemyn, Alexandrine; Ruckwardt, Tracy J; Graham, Barney S; Yassine, Hadi M... more authors ... less authors (2021)RSV is a major cause of lower respiratory infections among children, where no vaccine is available. The stabilized form of the fusion (F) protein, pre-F, is a leading vaccine candidate targeting different populations, ... -
Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer.
Zhang, Mengtian; Wang, Qin; Wan, Ka-Wai; Ahmed, Waqar; Phoenix, David A; Zhang, Zhirong; Elrayess, Mohamed A; Elhissi, Abdelbary; Sun, Xun... more authors ... less authors ( Elsevier , 2019 , Article)The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs). Elevated activity of cytochrome P4501A1 (CYP1A1) plays an important role in the metabolic ... -
Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
Al-Muraikhy, Shamma; Sellami, Maha; Domling, Alexander S; Rizwana, Najeha; Agouni, Abdelali; Al-Khelaifi, Fatima; Donati, Francesco; Botre, Francesco; Diboun, Ilhame; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2021 , Article)Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim ...