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Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
(
Taylor and Francis Ltd
, 2016 , Article)
Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ...
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
(
Blackwell Publishing Ltd
, 2016 , Article)
Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ...
Algal toxins and producers in the marine waters of Qatar, Arabian Gulf
(
Elsevier Ltd
, 2016 , Article)
Harmful Algal Bloom species are ubiquitous and their blooms occur in the Arabian Gulf. In this study, two cruises were performed in 2012 and 2013 to collect phytoplankton samples from 4 sites in the Arabian Gulf. Toxin ...
Magnetic mesoporous nanospheres anchored with LyP-1 as an efficient pancreatic cancer probe
(
Elsevier Ltd
, 2017 , Article)
Immobilization of a ligand that selectively interacts with cancer cells to nanomaterials can enhance their diagnostic and therapeutic efficiency. In this study, we firstly demonstrate the high expression of receptor for ...
Effects of electron acceptors on removal of antibiotic resistant Escherichia coli, resistance genes and class 1 integrons under anaerobic conditions
(
Elsevier B.V.
, 2016 , Article)
Anaerobic biotechnologies can effectively remove antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), but there is a need to better understand the mechanisms. Here we employ bioelectrochemical systems ...
Novel methodology for facile fabrication of nanofiltration membranes based on nucleophilic nature of polydopamine
(
Elsevier B.V.
, 2016 , Article)
Novel methodology for facilely fabricating nanofiltration (NF) composite membrane has been successfully developed by employing nucleophilic nature of polydopamine (PDA) chemistry. The self-polymerized PDA coating over ...
Controlled design of PtPd nanodendrite ornamented niobium oxynitride nanosheets for solar-driven water splitting
(
Royal Society of Chemistry
, 2018 , Article)
Developing efficient photocatalysts for the water splitting reaction is crucial in a fuel cell reaction. Herein, we present a facile road-map for one-pot fabrication of PtPd nanodendrite (ND) ornamented niobium oxynitride ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
(
Elsevier B.V.
, 2016 , Article)
This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ...