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Instrumentation of Flow-Through USP IV Dissolution Apparatus to Assess Poorly Soluble Basic Drug Products: a Technical Note
(
Springer New York LLC
, 2016 , Article)
Supersaturation and precipitation are common limitations encountered especially with poorly soluble basic drugs. The aims of this work were to explore the pattern of dissolution and precipitation of poorly soluble basic ...
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
(
Taylor and Francis Ltd
, 2016 , Article)
Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ...
Flavonol-carbon nanostructure hybrid systems: A DFT study on the interaction mechanism and UV/Vis features
(
Royal Society of Chemistry
, 2016 , Article)
Flavonols are a class of natural compounds with potential biological and pharmacological applications. They are also natural pigments responsible for the diversity of colors in plants. Flavonols offer the possibility of ...
Isolation and Physicochemical Characterization of Laccase from Ganoderma lucidum-CDBT1 Isolated from Its Native Habitat in Nepal
(
Hindawi Limited
, 2016 , Article)
At present, few organisms are known to and capable of naturally producing laccases and white rot fungi are one such group. In the
present study, three fungal species, namely, Ganoderma lucidum-CDBT1, Ganoderma japonicum, ...
Soft-shear induced phase-separated nanoparticle string-structures in polymer thin films
(
Royal Society of Chemistry
, 2016 , Article)
Application of shear stress has been shown to unidirectionally orient the microstructures of block copolymers and polymer blends. In the present work, we study the phase separation of a novel nanoparticle (NP)-polymer blend ...
Fuzzy intervention in biological phenomena
(
IEEE
, 2012 , Article)
An important objective of modeling biological phenomena is to develop therapeutic intervention strategies to move an undesirable state of a diseased network toward a more desirable one. Such transitions can be achieved by ...
Highly ordered nanoporous carbon films with tunable pore diameters and their excellent sensing properties
(
Wiley-VCH Verlag
, 2015 , Article)
Ordered porous carbon films with tunable pore diameters, immobilized with glucose oxidase (GOD) have been fabricated and employed for the construction of a biosensor for glucose molecules. The as-prepared porous films have ...
Freestanding eggshell membrane-based electrodes for high-performance supercapacitors and oxygen evolution reaction
(
Royal Society of Chemistry
, 2015 , Article)
A type of freestanding, light-weight eggshell membrane-based electrode is demonstrated for supercapacitors and for oxygen evolution reaction (OER) catalysis. As a widely available daily waste, eggshell membranes have unique ...
Magnetic mesoporous nanospheres anchored with LyP-1 as an efficient pancreatic cancer probe
(
Elsevier Ltd
, 2017 , Article)
Immobilization of a ligand that selectively interacts with cancer cells to nanomaterials can enhance their diagnostic and therapeutic efficiency. In this study, we firstly demonstrate the high expression of receptor for ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...