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SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2
(
MDPI
, 2020 , Article)
The recent outbreak of the Coronavirus disease 2019 (COVID-19) has quickly spread worldwide since its discovery in Wuhan city, China in December 2019. A comprehensive strategy, including surveillance, diagnostics, research, ...
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
(
Elsevier
, 2020 , Article)
ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: a systematic review
(
Elsevier
, 2020 , Article)
Backgroundthe recent outbreak of the coronavirus disease 2019 (COVID‐19) has quickly spread globally since its discovery in Wuhan, China, in December 2019. A comprehensive strategy, including surveillance, diagnostics, ...
Rapid Antibody-Based COVID-19 Mass Surveillance: Relevance, Challenges, and Prospects in a Pandemic and Post-Pandemic World.
(
MDPI
, 2020 , Article Review)
The aggressive outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) as COVID-19 (coronavirus disease-2019) pandemic demands rapid and simplified testing tools for its effective management. Increased ...
Loop-mediated isothermal amplification (Lamp): A rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of covid-19 pandemic
(
MDPI
, 2020 , Article)
The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. The most common molecular tests ...
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
(
Bentham Science Publishers
, 2020 , Article)
Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...
Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase
(
Taylor and Francis Ltd.
, 2020 , Article)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative representative of a severe respiratory illness resulted in widespread human infections and deaths in nearly all of the countries since late 2019. ...
The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets
(
Taylor and Francis Ltd.
, 2020 , Article)
Researchers have reported some useful information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to CoV disease 2019 (COVID-19). Several studies have been performed in order to develop ...
D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis
(
Frontiers Media
, 2020 , Article Review)
Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019,
COVID-19 has rapidly spread in virtually all countries, ...