Browsing College of Health Sciences by Title
Now showing items 1379-1398 of 1584
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Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, United States Abstract Chronic hyperglycemia is an important risk factor involved in the onset and progression of secondary complications of diabetes. ... -
Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway
( Elsevier , 2017 , Article)Prolonged hyperglycemia activates the formation of advanced glycation end-products (AGEs). Major dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the main precursors of AGEs and N(e)-(carboxymethyl)lysine ... -
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
( Elsevier , 2023 , Article)The solvent effects on the photochemical conversion rate of the photosensitizing drug diclofenac (DCF) were investigated using steady-state fluorescence spectroscopy. The spectral information obtained for the photochemical ... -
The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review
( Expert Reviews (formerly Future Drugs) / Taylor and Francis , 2020 , Article)To investigate the mutational spectrum in gene in Arab patients with Beta-Thalassemia (β-thal). Authors searched five databases (PubMed, Science Direct, Scopus, Web of Science, and Google Scholar) from the time of inception ... -
Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review.
( Wiley , 2018 , Article)Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the CFTR gene, with various clinical manifestations that affect pulmonary, digestive, exocrine and male reproductive functions as well ... -
Spectrum of mutations of familial hypercholesterolemia in the 22 Arab countries.
( Elsevier , 2018 , Article)Familial hypercholesterolemia (FH) is an inherited genetic disorder of lipid metabolism characterized by a high serum LDL-cholesterol profile and xanthoma formation, and FH increases the risk of premature atherosclerosis ... -
The Spectrum of Mutations of Homocystinuria in the MENA Region
( MDPI , 2020 , Article Review)Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ... -
Stage of change toward “9-a-day” not “5-a-day” is associated with lower body weight
( Emerald Publishing , 2017 , Article)Purpose- This study aimed to assess the students’ stage of change (SOC) for fruits and vegetables (FV) consumption using the 5-a-day and 9-a-day patterns; to validate a tool to measure SOC for consuming 5-a-day and 9-a-day ... -
Status and correlates of food and nutrition literacy among parents-adolescents’ dyads: findings from 10 Arab countries
( Frontiers Media SA , 2023 , Article)Background: Food literacy is capturing the attention worldwide and gaining traction in the Arab countries. Strengthening food and nutrition literacy among Arab teenagers are important promising empowering tools which can ... -
Status of continuous glucose monitoring use and management in tertiary hospitals of China: A cross-sectional study
( BMJ Publishing Group , 2023 , Article)Objective This study aims to reveal the use and management status of continuous glucose monitoring (CGM) in tertiary hospitals in China and to determine the potential factors affecting the application of CGM, based on which ... -
Status of the HIV epidemic in key populations in the Middle East and north Africa: knowns and unknowns.
( The Lancet HIV , 2022 , Article)The Middle East and north Africa is one of only two world regions where HIV incidence is on the rise, with most infections occurring among key populations: people who inject drugs, men who have sex with men, and female sex ... -
Strategies to enhance graphic and results interpretation of a regression-based approach for method comparison studies.
( Future Science Ltd , 2017 , Article)To improve the effectiveness of a previous regression-based approach for the assessment of the agreement between different analytical methods, two modifications/integrations to the original scheme by means of log10 ... -
Structural Analysis of G1691S Variant in the Human Filamin B Gene Responsible for Larsen Syndrome: A Comparative Computational Approach
( Wiley Periodicals, Inc , 2017 , Article)Larsen syndrome (LRS) is a rare genetic disease associated with variable manifestations including skeletal malformations, dislocations of the large joints, and notable changes in facial and limb features. Genetic variants ... -
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
( Wiley , 2018 , Article)Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper ... -
Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope
( Elsevier (Cell Press) , 2017 , Article)The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies ... -
Structural modeling of p.V31F variant in the aspartoacylase gene.
( Springer Verlag , 2016 , Article)Aspartoacylase (ASPA) is an abundant enzyme in the brain, which catalyzes the conversion of N-acetylaspartate into acetate and aspartate, deficiency in its activity leads to degeneration of the white matter of the brain ... -
Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
( Frontiers Media , 2021 , Article)The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ... -
Student perspectives on the integration of artificial intelligence into healthcare services
( SAGE Publications Inc. , 2023 , Article)Background: Healthcare workers are often overworked, underfunded, and face many challenges. Integration of artificial intelligence into healthcare service provision can tackle these challenges by relieving burdens on ... -
Students' perceptions of a university 'No Smoking' policy and barriers to implementation: a cross- sectional study.
(2021 , Article)Effective policies are an important tool for reducing tobacco use. We examine student perceptions of the existing no-smoking policy in the country's largest national university and identify perceived barriers to its ... -
Study protocol: Mother and Infant Nutritional Assessment (MINA) cohort study in Qatar and Lebanon
( BioMed Central , 2016 , Article)Background The Middle East and North Africa region harbors significant proportions of stunting and wasting coupled with surging rates of non-communicable diseases (NCDs). Recent evidence identified nutrition during the ...