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Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
(
MedCrave
, 2016 , Article)
Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ...
Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
(
Longdom
, 2019 , Article)
Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in
transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant
association ...
Neutrophil Gelatinase Associated Lipocalin: Is not an Early Marker Inductor for Diabetic Nephropathy in Qatari Population
(
BJSTR
, 2019 , Article)
Background: The WHO Global Report on Diabetes (2016) showed that the number
of diabetic patients quadrupled between 1980 and 2016, while causing the death of 1.5
million people. While the global prevalence of diabetes ...
Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases
(2016 , Poster)
Background:
Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ...
The Relationship Between Leptin and PCOS
(
De Gruyter
, 2014 , Conference Paper)
Background: The ob gene produces a leptin hormone that works
as a satiety signal to the hypothalamus. Leptin may have a role in polycystic ovary syndrome (PCOS) via its role on obesity and insulin resistance.
Materials ...
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
(
Hindawi Publishing Corporation
, 2015 , Article)
Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates
in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ...
Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles
(
Elsevier B.V.
, 2013 , Article)
Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and ...
The Dual Role of Paramagnetic Particles for Integrated Lysis and Measurement in a Rapid Immunoassay for Intracellular Proteins
(
IEEE
, 2013 , Article)
Abstract—A novel, integrated lysis and immunoassay method-
ology and system for intracellular protein measurement are de-
scribed. The method uses paramagnetic particles both as a lysis
agent and assay label resulting ...
TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects
(2020 , Article)
Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, ...
New markers for the detection of polycystic ovary syndrome
(
MedCrave Group
, 2019 , Article)
Polycystic Ovary Syndrome (PCOS) is a highly prevalent, complex genetic disorder of the endocrine system in women. Alterations that occur in women with PCOS can be due to several predisposing factors; among these contributors ...