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Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
(
Elsevier
, 2016 , Article)
Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ...
Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway.
(
MDPI
, 2019 , Article)
Despite pharmacotherapeutic advances, cardiovascular disease (CVD) remains the primary cause of global mortality. Alternative approaches, such as herbal medicine, continue to be sought to reduce this burden. is recognized ...
Cadmium induces migration of colon cancer cells: Roles of reactive oxygen species, p38 and cyclooxygenase-2
(
Cell Physiol Biochem Press GmbH & Co KG
, 2019 , Article)
Background/Aims: Cadmium (Cd) is a heavy metal contaminant whose toxicity is associated with colorectal cancer (CRC). However, the underlying molecular mechanisms of Cd-induced CRC malignancy remain obscure. Methods: A ...
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
(
Elsevier
, 2022 , Article)
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ...
Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros
(
MDPI AG
, 2021 , Article)
Pancreatic cancer (PC) is the fourth leading cause of all cancer-related deaths. Despite major improvements in treating PC, low survival rate remains a major challenge, indicating the need for alternative approaches, ...
Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations.
(
MDPI
, 2023 , Article Review)
Adverse pregnancy outcomes are considered significant health risks for pregnant women and their offspring during pregnancy and throughout their lifespan. These outcomes lead to a perturbated in-utero environment that impacts ...
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
(
Portland Press Ltd
, 2020 , Article Review)
Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ...
Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
(
Hindawi Limited
, 2017 , Article)
Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. Atherosclerosis is a CVD characterized by plaque formation resulting from inflammation-induced insults to endothelial cells, monocytes, and ...
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
(
Elsevier
, 2016 , Article)
Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ...