Browsing Biomedical Sciences by Author "Eid, Ali H."
Now showing items 1-20 of 36
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An updated overview of cyanidins for chemoprevention and cancer therapy
Posadino, Anna Maria; Giordo, Roberta; Ramli, Iman; Zayed, Hatem; Nasrallah, Gheyath K.; Wehbe, Zena; Eid, Ali H.; Gürer, Eda Sönmez; Kennedy, John F.; Aldahish, Afaf Ahmed; Calina, Daniela; Razis, Ahmad Faizal Abdull; Modu, Babagana; Habtemariam, Solomon; Sharifi-Rad, Javad; Pintus, Gianfranco; Cho, William C.... more authors ... less authors ( Elsevier , 2023 , Article Review)Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ... -
Antihypertensive indigenous lebanese plants: Ethnopharmacology and a clinical trial
Samaha, Ali A.; Fawaz, Mirna; Salami, Ali; Baydoun, Safaa; Eid, Ali H. ( MDPI AG , 2019 , Article)Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
Aramouni, Karl; Assaf, Roland; Shaito, Abdullah; Fardoun, Manal; Al-Asmakh, Maha; Sahebkar, Amirhossein; Eid, Ali H.... more authors ... less authors ( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Swapna, Thomas; Ouhtit, Allal; Al Khatib, Hebah A.; Eid, Ali H.; Mathew, Shilu; Nasrallah, Gheyath K.; Emara, Mohamed M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Cadmium induces migration of colon cancer cells: Roles of reactive oxygen species, p38 and cyclooxygenase-2
Naji, Sara; Issa, Khodr; Eid, Assaad; Iratni, Rabah; Eid, Ali H. ( Cell Physiol Biochem Press GmbH & Co KG , 2019 , Article)Background/Aims: Cadmium (Cd) is a heavy metal contaminant whose toxicity is associated with colorectal cancer (CRC). However, the underlying molecular mechanisms of Cd-induced CRC malignancy remain obscure. Methods: A ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
Nasarallah, Gheyath K.; Fakhroo, Aisha D.; Khan, Taushif; Cyprian, Farhan S.; Al Ali, Fatima; Ata, Manar M.A.; Taleb, Sara; Zedan, Hadeel T.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Hssain, Ali A.; Eid, Ali H.; Abu-Raddad, Laith J.; Al-Khal, Abdullatif; Al Thani, Asmaa A.; Marr, Nico; Yassine, Hadi M.... more authors ... less authors ( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Drug repurposing in cancer: Now and beyond
Eid, Ali H. (2021 , Other)No Abdtract -
Drug repurposing in neurodegenerative and cardiovascular diseases
Eid, Ali H. ( Bentham Science Publishers , 2021 , Other)No Abstract -
Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis
Jamialahmadi, Tannaz; Reiner, Željko; Alidadi, Mona; Almahmeed, Wael; Kesharwani, Prashant; Al-Rasadi, Khalid; Eid, Ali H.; Rizzo, Manfredi; Sahebkar, Amirhossein... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: Obesity, and in particular extreme obesity, as a global health problem is an important risk factor for many diseases, including atherosclerotic cardiovascular disease (ACVD). Bariatric surgery might stop or ... -
Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations.
Ramli, Iman; Posadino, Anna Maria; Giordo, Roberta; Fenu, Grazia; Fardoun, Manal; Iratni, Rabah; Eid, Ali H; Zayed, Hatem; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2023 , Article Review)Adverse pregnancy outcomes are considered significant health risks for pregnant women and their offspring during pregnancy and throughout their lifespan. These outcomes lead to a perturbated in-utero environment that impacts ... -
Estrogen and Bisphenol A in Hypertension
Wehbe, Zena; Nasser, Suzanne A.; El-Yazbi, Ahmed; Nasreddine, Salam; Eid, Ali H. ( Springer , 2020 , Article Review)Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ... -
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
Fardoun, Manal M.; Issa, Khodr; Maaliki, Dina; Nasser, Suzanne A.; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Elsevier , 2020 , Article)Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ... -
Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.
Posadino, Anna Maria; Giordo, Roberta; Cossu, Annalisa; Nasrallah, Gheyath K; Shaito, Abdullah; Abou-Saleh, Haissam; Eid, Ali H; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2019 , Article)Dietary intake of natural antioxidants is thought to impart protection against oxidative-associated cardiovascular diseases. Despite many in vivo studies and clinical trials, this issue has not been conclusively resolved. ... -
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
Fardoun, Manal Muin; Maaliki, Dina; Halabi, Nabil; Iratni, Rabah; Bitto, Alessandra; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Portland Press Ltd , 2020 , Article Review)Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ... -
Flavonoids in hypertension: a brief review of the underlying mechanisms.
Maaliki, Dina; Shaito, Abdullah A; Pintus, Gianfranco; El-Yazbi, Ahmed; Eid, Ali H ( Elsevier , 2019 , Article)Flavonoids are a diverse group of bioactive polyphenolic compounds abundant in dietary plants and herbs. Regular consumption of flavonoids exerts cardio-vasculoprotective effects and may reduce the onset or progression of ... -
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
Shaito, Abdullah; Thuan, Duong Thi Bich; Phu, Hoa Thi; Nguyen, Thi Hieu Dung; Hasan, Hiba; Halabi, Sarah; Abdelhady, Samar; Nasrallah, Gheyath K.; Eid, Ali H.; Pintus, Gianfranco... more authors ... less authors ( Frontiers Media S.A. , 2020 , Article)Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing prevalence. They remain the leading causes of morbidity and mortality worldwide. The use of medicinal herbs continues to be an ... -
Herbal medicine for slowing aging and aging-associated conditions: Efficacy, mechanisms and safety
Phu, Hoa T.; Thuan, Duong T.B.; Nguyen, Thi H.D.; Posadino, Anna M.; Eid, Ali H.; Pintus, Gianfranco... more authors ... less authors ( Bentham , 2020 , Article)Aging and aging-associated diseases are issues with unsatisfactory answers in the medical field. Aging causes important physical changes which, even in the absence of the usual risk factors, render the cardiovascular system ... -
Inflammation and hypertension: Underlying mechanisms and emerging understandings
Aboukhater, Diana; Morad, Bassel; Nasrallah, Nadim; Nasser, Suzanne A.; Sahebkar, Amirhossein; Kobeissy, Firas; Boudaka, Ammar; Eid, Ali H.... more authors ... less authors ( wiley online library , 2023 , Article Review)Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ... -
Inflammatory basis of atherosclerosis: Modulation by sex hormones
Nasser, Suzanne A.; Afify, Elham A.; Kobeissy, Firas; Hamam, Bassam; Eid, Ali H.; El-Mas, Mahmoud M.... more authors ... less authors ( Bentham Science Publishers , 2021 , Other)Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of death globally. Several lines of evidence are supportive of the contributory role of vascular inflammation in atherosclerosis. Di-verse immune ... -
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
Eid, Ali H; El-Yazbi, Ahmed F; Zouein, Fouad; Arredouani, Abdelilah; Ouhtit, Allal; Rahman, Md M; Zayed, Hatem; Pintus, Gianfranco; Abou-Saleh, Haissam... more authors ... less authors ( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ...