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Now showing items 31-40 of 58
Platforms Exploited for SARS-CoV-2 Vaccine Development.
(
MDPI
, 2020 , Article Review)
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells ...
Nanomedicine as a Potential Tool against Monkeypox.
(
MDPI
, 2023 , Article Review)
Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ...
Pandemic COVID-19 caused by SARS-CoV-2: genetic structure, vaccination, and therapeutic approaches
(
Springer
, 2021 , Article Review)
We give a summary of SARS-genetic CoV-2’s structure and evolution, as well as current attempts to develop efficient vaccine and treatment methods for SARS-CoV-2 infection, in this article. Most therapeutic strategies are ...
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
(
Springer
, 2022 , Article Review)
EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ...
Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors
(
Springer
, 2023 , Article Review)
Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent one type of new-generation type 2 diabetes (T2DM) drug treatment. The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering ...
Implications of Gut Microbiota in Epithelial–Mesenchymal Transition and Cancer Progression: A Concise Review
(
MDPI
, 2022 , Article Review)
Advancement in the development of molecular sequencing platforms has identified infectious bacteria or viruses that trigger the dysregulation of a set of genes inducing the epithelial– mesenchymal transition (EMT) event. ...
The therapeutic potential of matcha tea: A critical review on human and animal studies
(
Elsevier
, 2023 , Article Review)
Matcha is a powdered form of Japanese green tea that has been gaining global popularity recently. Matcha tea has various health benefits, including an enhancing effect on cognitive function, cardio-metabolic health, and ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
Statistical methods and resources for biomarker discovery using metabolomics.
(
BMC
, 2023 , Article Review)
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and disease. Metabolic profiles provide a close insight into physiological states and are highly volatile to genetic and environmental ...
Biological applications of imiquimod analogues: An update (Review)
(
Spandidos Publications
, 2023 , Article Review)
The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ...