بحث بسيط
السجلات المعروضة 1 -- 2 من 2
Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.
(
American Society for Microbiology
, 2019 , Article)
Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ...
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses.
(
Nature Research
, 2020 , Article)
The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the ...