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Connecting the dots between PubMed abstracts
(
Public Library of Science
, 2012 , Article)
Background: There are now a multitude of articles published in a diversity of journals providing information about genes, proteins, pathways, and diseases. Each article investigates subsets of a biological process, but to ...
Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits
(
Scientific Research Publishing
, 2015 , Article)
Background: Previous studies showed that atherosclerotic plaque vulnerability was related with microparticles (MPs)-vesicles larger than 100 nm, which released MMP9 collagenase. In our pre- vious study, intramuscular ...
A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
(
Elsevier
, 2017 , Article)
Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its ...
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
(
MDPI AG
, 2019 , Article)
Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ...
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
(
Public Library of Science
, 2013 , Article)
The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. FITC-dextran flux across the REC monolayers and electrical ...
Targeting inflammatory components in neuropathic pain: The analgesic effect of thymulin related peptide
(
Elsevier Ireland Ltd
, 2019 , Article Review)
Neuropathic pain is considered to be pathological in nature and has been shown to involve, at least partially, dysregulated inflammatory processes. It is a severe chronic disease that can develop following lesions to the ...
Bone benefits of fish oil supplementation depend on its EPA and DHA content
(
MDPI AG
, 2019 , Article)
The preventive effect of high-dose (9%) regular-fish oil (FO) against bone loss during aging has been demonstrated, but the effects of a low-dose (1%–4%) of a highly purified concentrated FO (CFO) has not been elucidated. ...
Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders
(
Society for Biomedical Diabetes Research
, 2019 , Article)
BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ...
Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury
(
Scientific Research Publishing
, 2019 , Article Review)
Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...
Progressive circuit resistance training improves inflammatory biomarkers and insulin resistance in obese men
(
Elsevier Inc.
, 2019 , Article)
Circuit resistance training (CRT) is a time-efficient exercise modality for improving skeletal muscle and cardiovascular fitness. But the beneficial role of CRT in obese individuals is still not well understood. This study ...