Browsing Pharmacy Research by Subject "chemistry"
Now showing items 1-4 of 4
-
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
( Elsevier Masson SAS , 2016 , Article)A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ... -
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
( Elsevier B.V. , 2016 , Article)This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ... -
Instrumentation of Flow-Through USP IV Dissolution Apparatus to Assess Poorly Soluble Basic Drug Products: a Technical Note
( Springer New York LLC , 2016 , Article)Supersaturation and precipitation are common limitations encountered especially with poorly soluble basic drugs. The aims of this work were to explore the pattern of dissolution and precipitation of poorly soluble basic ... -
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
( S. Karger AG , 2016 , Conference Paper)This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ...