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3D printed nanocomposites for tailored cardiovascular tissue constructs: A minireview
(
Elsevier B.V.
, 2021 , Article)
Cardiovascular diseases (CVD) with escalating death rates pose one of the greatest threats to global health and well-being. Thus, developing effective interventions to combat CVD are of critical importance. 3D printing ...
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
(
Elsevier B.V.
, 2021 , Article)
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ...
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy ...
Mucoadhesive chitosan derivatives as novel drug carriers
(
Bentham Science Publishers B.V.
, 2015 , Article)
Chitosan on its own is a well-established natural polymer and is widely regarded as a biodegradable, biocompatible and nontoxic material for drug delivery applications. Although unmodified chitosan has some mucoadhesive ...
Porcine cholecyst derived extracellular matrix (p-CEM) for reconstruction of full thickness skin wounds in rats
(
Elsevier GmbH
, 2015 , Article)
An acellular cholecyst derived extracellular matrix (p-CEM) of porcine origin was prepared using anionic biological detergent. Healing potential of (p-CEM) was compared with commercially available collagen sheet (b-CS) and ...
Bovine reticulum derived extracellular matrix (b-REM) for reconstruction of full thickness skin wounds in rats
(
Elsevier GmbH
, 2016 , Article)
Thirty six clinically healthy adult Wistar rats of either sex were used in the study and randomly divided into three groups having twelve animals in each group. Under general anesthesia, a full-thickness skin wound (20 ? ...
Nanoparticles in tissue engineering: Applications, challenges and prospects
(
Dove Medical Press Ltd.
, 2018 , Article)
Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science and medical biology that aims to develop biological substitutes to repair, replace, retain, or enhance tissue and organ-level ...
Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats
(
Hindawi Limited
, 2016 , Article)
An acellular cholecyst derived extracellular matrix (b-CEM) of bubaline origin was prepared using anionic biological detergent. Healing potential of b-CEM was compared with commercially available collagen sheet (b-CS) and ...
Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
(
Dove Medical Press Ltd.
, 2019 , Article)
Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ...
A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin
(
Taylor and Francis Ltd.
, 2021 , Article)
The widespread antigenic changes lead to the emergence of a new type of coronavirus (CoV) called as severe acute respiratory syndrome (SARS)-CoV-2 that is immunologically different from the previous circulating species. ...