تصفح College of Medicine حسب العنوان
السجلات المعروضة 1006 -- 1025 من 1314
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Proteomic analysis of T. qataranse exposed to lead (Pb) stress reveal new proteins with potential roles in Pb tolerance and detoxification mechanism
( Frontiers Media , 2022 , Article)Soil lead (Pb) contamination is one of the environmental problems facing the modern world. Sources of Pb in soil include industrial activities such as mining and smelting processes, agricultural activities such as application ... -
Proteomic analysis of the endometrium during early pregnancy in the domestic pig.
( CSIRO Publishing , 2017 , Article)Reproductive processes in domestic pigs have been studied extensively. Pigs are one of the main sources of meat for human consumption and are an established model for investigations into mammalian, including human, ... -
Proteomic profile alterations in porcine conceptuses during early stages of development
( Elsevier , 2021 , Article)The dynamic embryo development during the early stages of gestation requires precise molecular changes, including proteomic ones. We aimed to find unique proteins for porcine conceptuses specifically during the peri-implantation ... -
Proteomic profile in congenital microcephaly
( Qatar University Press , 2021 , Poster)Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify ... -
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
( Karger Publishers , 2018 , Article)The aim of this study was to identify differences in proteome profiles of diffuse large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the search for new markers and drug targets. Six DLBCL, with ... -
Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The accurate diagnosis of small-cell lung cancer (SCLC) is crucial, as treatment strategies differ from those of other lung cancers. This systematic review aims to identify proteins differentially expressed in SCLC compared ... -
Proteomics of transforming growth factor ?1 (TGF ?1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2? in TGF ?1-dependent p53 phosphorylation at Ser392
( Morion LLC , 2019 , Article)Aim: Transforming growth factor ?1 (TGF ?1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic ... -
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
( Elsevier , 2020 , Article Review)ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ... -
Psychiatric inpatients' views of their mental health, and their experience of social change, during the pandemic: A report from Qatar
( John Wiley and Sons Inc , 2022 , Article)What is known on the subject?: There is only limited information on how the COVID-19 pandemic has affected people diagnosed with mental health disorders, especially people admitted to psychiatric wards. We surveyed the ... -
Psychological impact of the COVID-19 pandemic within institutional quarantine and isolation centres and its sociodemographic correlates in Qatar: A cross-sectional study
( BMJ Publishing Group , 2021 , Article)Setting The State of Qatar has had one of the highest COVID-19 infection rates globally and has used state-managed quarantine and isolation centres to limit the spread of infection. Quarantine and isolation have been shown ... -
Psychosocial Aspects of Female Breast Cancer in the Middle East and North Africa.
( MDPI , 2020 , Article)Breast cancer, the most common cancer among women in the Middle East and North Africa (MENA) region, is associated with social and psychological implications deriving from women's socio-cultural contexts. Examining 74 ... -
Psychosocial treatments for substance use disorders
( Nova Science Publishers, Inc. , 2022 , Book chapter)Worldwide use of illicit drugs is increasing, and substance use disorders (SUDs) have become a significant mental health problem in the West. Although the majority of young people do not use illicit drugs and of those who ... -
Psychotic-like experiences among university female students in Qatar: A qualitative-phenomenological study
( Frontiers Media , 2022 , Article)Background and aims: Psychotic-like experiences (PLEs) are hallucinatory or delusional experiences that fall below the threshold of a diagnosable psychotic disorder. Although PLEs are common across the spectrum of psychiatric ... -
PTRH2 is Necessary for Purkinje Cell Differentiation and Survival and its Loss Recapitulates Progressive Cerebellar Atrophy and Ataxia Seen in IMNEPD Patients
( Springer , 2022 , Article)Homozygous variants in the peptidyl-tRNA hydrolase 2 gene (PTRH2) cause infantile-onset multisystem neurologic, endocrine, and pancreatic disease. The objective is to delineate the mechanisms underlying the core cerebellar ... -
Pyocyanin pigment from Pseudomonas aeruginosa modulates innate immune defenses in macrophages
( Qatar University Press , 2021 , Poster)Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen. The gram-negative bacillus, commonly associated with hospital-acquired infections, utilizes the host's impaired immune responses to establish ... -
Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype
( Elsevier , 2022 , Article)The prevalence of homocystinuria in Qatar is 1:1800, mainly due to a founder missense mutation p.R336C. • The cystathionine beta-synthase (CBS) R336C mutant was bacterially expressed, purified and its molecular properties ... -
‘Q-Storming’ to identify challenges and opportunities for integrating health and climate adaptation measures in Africa
( Elsevier , 2023 , Article)Introduction: Climate factors influence the state of human health and wellbeing. Climate-related threats are particularly being experienced by vulnerable populations in Africa. A Question (Q)-Storming session was convened ... -
Qatar Healthcare Workers' COVID-19 Vaccine Hesitancy and Attitudes: A National Cross-Sectional Survey
( Frontiers Media S.A. , 2021 , Article)Introduction: Healthcare workers are the critical frontline workforce of the COVD-19 pandemic and are considered a target group for vaccination. Hesitancy to vaccinate is a major concern that can jeopardize the vaccination ... -
QCovSML: A reliable COVID-19 detection system using CBC biomarkers by a stacking machine learning model
( Elsevier , 2022 , Article)The reverse transcription-polymerase chain reaction (RT-PCR) test is considered the current gold standard for the detection of coronavirus disease (COVID-19), although it suffers from some shortcomings, namely comparatively ... -
QTc evaluation in COVID-19 patients treated with chloroquine/hydroxychloroquine: A letter to the editor
( Wiley-Blackwell , 2020 , Other)We read with interest Monzani et al's report1 on QT pro-longation in COVID-19 patients on treatment with chloro-quine/hydroxychloroquine (CQ/HCQ). Her report highlights the therapeutic morbidities ...
