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COVID-19 in a pregnant patient with beta-thalassemia major: A case report
(
Wiley-Blackwell
, 2021 , Article)
Further studies are needed on this unique population to better manage them and increase their chances of normal pregnancy and fewer complications and more favorable outcomes.
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
(
American Society for Pharmacology and Experimental Therapy
, 2021 , Article Review)
ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ...
The COVID-19 pandemic and healthcare systems in Africa: A scoping review of preparedness, impact and response
(
BMJ Publishing Group
, 2021 , Article)
Background The COVID-19 pandemic has overwhelmed health systems in both developed and developing nations alike. Africa has one of the weakest health systems globally, but there is limited evidence on how the region is ...
A protocol for the detection of genetic markers in saliva by polymerase chain reaction without a nucleic acid purifi cation step: Examples of SARS-CoV-2 and GAPDH markers
(
Danylo Halytskyi Lviv National Medical University
, 2021 , Article)
Introduction. Polymerase chain reaction (PCR)-based diagnostic tests use purifi ed nucleic acids (NAs) from clinical samples. The NAs purifi cation step adds time, cost, and aff ects the quality of testing. The objective ...
Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon
(
MDPI
, 2021 , Article)
Objective: This study was designed to determine the efficacy of ivermectin, an FDA-approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among asymptomatic subjects that tested positive ...
Could antigen presenting cells represent a protective element during sars-cov-2 infection in children?
(
MDPI
, 2021 , Article)
Antigen Presenting Cells (APC) are immune cells that recognize, process, and present antigens to lymphocytes. APCs are among the earliest immune responders against an antigen. Thus, in patients with COVID-19, a disease ...
Clinical characteristics of 51,815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings: Priority populations for vaccination
(
Elsevier
, 2021 , Article)
We read with interest Brendish et al. study on the comparison between patients with SARS-CoV-2 positive and negative swab results.1
The study compared the clinical characteristics of adult hospitalised patients with ...
Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19
(
Frontiers
, 2021 , Article)
Coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the most concerning health problem worldwide. SARS-CoV-2 infects cells by binding to ...
Prevalence of Venous Thromboembolism in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis
(
Frontiers Media S.A.
, 2021 , Article)
Background: Recent studies revealed a high prevalence of venous thromboembolism (VTE) events in coronavirus disease 2019 (COVID-19) patients, especially in those who are critically ill. Available studies report varying ...
Mental wellbeing of frontline healthcare workers during COVID-19 pandemic in Qatar
(
Elsevier
, 2021 , Other)
The Coronavirus disease 2019 (COVID-19) began with initial cases in China in December 2019 and by January 2020, World Health Organization (WHO) declared it as a Public Health Emergency of International Concern (WHO ...