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Visfatin : An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases
(
Wiley
, 2021 , Article)
Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been implicated in vascular remodeling, vascular ...
Serum 25-Hydroxyvitamin D Is Inversely Associated with Monocyte Percentage to HDL Cholesterol Ratio among Young Healthy Adults in Qatar.
(2020)
Low serum 25-hydroxyvitamin D [25(OH)D] is linked to an altered lipid profile. Monocytes play an important role in inflammation and lipid metabolism. Recently, monocyte percentage to HDL-cholesterol ratio (MHR) has emerged ...
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
(
IMR Press
, 2022 , Article Review)
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ...
Metabolic aspects of surgical subcutaneous fat removal: an umbrella review and implications for future research.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2022 , Article Review)
Although obesity is a preventable disease, maintaining a normal body weight can be very challenging and difficult, which has led to a significant increase in the demand for surgical subcutaneous fat removal (SSFR) to improve ...
A possible role for inducible arginase isoform (AI) in the pathogenesis of chronic venous leg ulcer
(
Wiley
, 2020 , Article)
Chronic venous ulcer (CVU) is a major cause of chronic wounds of lower extremities and presents a significant financial and resource burden to health care systems worldwide. Defects in the vasculature, matrix deposition, ...
The Effects of Statin Treatment on Serum Ferritin Levels: A Systematic Review and Meta-Analysis
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background: Statins are the most widely used drugs for decreasing elevated serum LDL-cholesterol (LDL-C) and thus for the prevention of atherosclerotic cardiovascular disease (ASCVD), but they have also some pleiotropic ...
Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations
(
De Gruyter Open Ltd
, 2021 , Article Review)
Abdominal aortic aneurysm (AAA) is a complex degenerative vascular disease, with considerable morbidity and mortality rates among the elderly population. The mortality of AAA is related to aneurysm expansion (the enlargement ...
Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic ...
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the ...
Human antigen R: Exploring its inflammatory response impact and significance in cardiometabolic disorders
(
Wiley
, 2024 , Article Review)
RNA-binding proteins (RBPs) play a crucial role in the regulation of posttranscriptional RNA networks, which can undergo dysregulation in many pathological conditions. Human antigen R (HuR) is a highly researched RBP that ...