Search
Now showing items 1-10 of 10
Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
(
Hindawi
, 2017 , Article)
Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, ...
Garlic for cardiovascular disease: Prevention or treatment?
(
Bentham Science Publishers B.V.
, 2017 , Article Review)
Cardiovascular disease (CVD) is the leading cause of global mortality with a substantial economic impact. The annual deaths are expected to increase in the next decade. An array of dietary supplements is being used by ...
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ...
Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ...
Pharmacological and antioxidant activities of rhus coriaria l. (sumac)
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in ...
Adipose tissue immunomodulation: A novel therapeutic approach in cardiovascular and metabolic diseases
(
Frontiers Media
, 2020 , Article)
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As the main storage pool of lipids, ...
Covid-19 in pediatric patients: A focus on CHD patients
(
Frontiers Media S.A.
, 2020 , Article)
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ...
Hydroxychloroquine in COVID-19 Patients: Pros and Cons
(
Frontiers Media S.A.
, 2020 , Article)
The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach ...
Role of methylglyoxal in diabetic cardiovascular and kidney diseases: Insights from basic science for application into clinical practice
(
Bentham Science Publishers
, 2018 , Other)
Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. ...
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ...