تصفح Biomedical Research Center Research حسب العنوان

السجلات المعروضة 221 -- 240 من 668

    • Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines 

      Fernandes, Queenie; Inchakalody, Varghese Philipose; Merhi, Maysaloun; Mestiri, Sarra; Taib, Nassiba; ... more authors ( Taylor and Francis , 2022 , Article)
      The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing ...

    • Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential 

      Kheraldine, Hadeel; Rachid, Ousama; M Habib, Abdella; Al Moustafa, Ala-Eddin; F. Benter, Ibrahim ( Elsevier , 2021 , Article)
      Drug delivery systems or vectors are usually needed to improve the bioavailability and effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an organ, tissue or cellular level. However, emerging ...

    • EndMT regulation by small RNAs in diabetes-associated fibrotic conditions: potential link with oxidative stress 

      Giordo, Roberta; Mohammed, Yusra; Allam, Hilda; Abusnana, Salah; Pappalardo, Lucia; ... more authors ( Frontiers Media , 2021 , Article)
      Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ dysfunction, disability, and increased mortality. ...

    • Enhancing the sensitivity of rapid antigen detection test (RADT) of different SARS-CoV-2 variants and lineages using fluorescence-labeled antibodies and a fluorescent meter 

      Gheyath K., Nasrallah; Ali, Fatma; Younes, Salma; Al Khatib, Heba A.; Al-Thani, Asmaa A.; ... more authors ( Elsevier , 2023 , Article)
      RT-qPCR is considered the gold standard for diagnosis of COVID-19; however, it is laborious, time-consuming, and expensive. RADTs have evolved recently as relatively inexpensive methods to address these shortcomings, but ...

    • Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host 

      Hoda, Najjar; Al-Ashmar, Sarah; Qush, Abeer; Al-Asmar, Jawaher; Rashwan, Sara; ... more authors ( Elsevier , 2022 , Article)
      On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ...

    • Epac as a tractable therapeutic target 

      Hasan, Slika; Mansour, Hadi; Nasser, Suzanne A.; Shaito, Abdullah; Kobeissy, Firas; ... more authors ( Elsevier , 2023 , Article)
      In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein kinase A (PKA) pathway. Since then, cAMP has received increasing ...

    • Epidemiological and genetic characterization of pH1N1 and H3N2 influenza viruses circulated in MENA region during 2009-2017. 

      Al Khatib, Hebah A; Al Thani, Asmaa A; Gallouzi, Imed; Yassine, Hadi M ( BMC , 2019 , Article)
      Influenza surveillance is necessary for detection of emerging variants of epidemiologic and clinical significance. This study describes the epidemiology of influenza types A and B, and molecular characteristics of surface ...

    • Epidemiological impact of prioritising SARS-CoV-2 vaccination by antibody status: Mathematical modelling analyses 

      Ayoub, H.H.; Ayoub, Houssein H.; Chemaitelly, Hiam; Makhoul, Monia; Al Kanaani, Zaina; ... more authors ( BMJ Publishing Group , 2021 , Article)
      Background Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient ...

    • Epidemiological, Molecular, and Clinical Features of Norovirus Infections among Pediatric Patients in Qatar 

      Mathew, Shilu; Alansari, Khalid; Smatti, Maria K.; Zaraket, Hassan; Al Thani, Asmaa A.; ... more authors ( MDPI , 2019 , Article)
      Abstract: Background: Norovirus (NoV) is recognized as the second most important etiological agent leading to acute gastroenteritis globally. In order to determine the burden and characteristics of NoV infections in children ...

    • Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar 

      Mathew, Shilu; Al Ansari, Khalid; Al Thani, Asmaa A; Zaraket, Hassan; Yassine, Hadi M ( Springer , 2021 , Article)
      Acute gastroenteritis (AGE) remains a major cause of diarrhea in developing and developed countries. Rotavirus (RV) is a leading cause of severe pediatric diarrhea worldwide. Here we report on the prevalence of circulating ...

    • Epidemiology of respiratory infections among adults in Qatar (2012-2017). 

      Al-Romaihi, Hamad Eid; Smatti, Maria K; Ganesan, Nandakumar; Nadeem, Shazia; Farag, Elmoubasher; ... more authors ( Public Library of Science , 2019 , Article)
      Limited data is available about the etiology of influenza like illnesses (ILIs) in Qatar. This study aimed at providing preliminary estimates of influenza and other respiratory infections circulating among adults in Qatar. ...

    • Epidemiology of SARS-CoV2 in Qatar's primary care population aged 10 years and above 

      Syed, Mohamed Ahmed; Al Nuaimi, Ahmed Sameer; A/Qotba, Hamda Abdulla; Nasrallah, Gheyath K; Althani, Asmaa A; ... more authors ( BMC , 2021 , Article)
      There is an urgent need to elucidate the epidemiology of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and characterize its potential impact. Investing in characterising the SARS-CoV2 will help plan and ...

    • Epidemiology Profile of Viral Meningitis Infections Among Patients in Qatar (2015-2018) 

      Mathew, Shilu; Al Khatib, Hebah A; Al Ansari, Khalid; Nader, Joanne; Nasrallah, Gheyath K; ... more authors ( Frontiers Media , 2021 , Article)
      Little is known about the etiology of meningitis in the MENA region, including Qatar. Viral agents are considered the major cause for meningitis worldwide. Here, we present primary data about the etiology and clinical and ...

    • Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression. 

      Cyprian, Farhan S; Al-Farsi, Halema F; Vranic, Semir; Akhtar, Saghir; Al Moustafa, Ala-Eddin ( Frontiers Media , 2018 , Article Review)
      Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ...

    • Epstein-Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study. 

      Al-Antary, Noor; Farghaly, Hanan; Aboulkassim, Tahar; Yasmeen, Amber; Akil, Nizar; ... more authors ( Taylor & Francis , 2017 , Article)
      Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential ...

    • Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update 

      Smatti, Maria K.; Al-Sadeq, Duaa W.; Ali, Nadima H.; Pintus, Gianfranco; Abou-Saleh, Haissam; ... more authors ( Frontiers Medi , 2018 , Article Review)
      The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to ...

    • Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y 

      Sartelli, M.; Weber, D. G.; Ruppé, E.; Bassetti, M.; Wright, B. J.; ... more authors ( BioMed Central Ltd. , 2017 , Other)
      The original article [1] contains an error whereby a co-author, Boris Sakakushev has their family name spelt incorrectly as 'Sakakhushev'. The authors would therefore like it known that the correct spelling of the family ...

    • Erratum: Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar (Virology Journal (2016) 13:1 DOI: 10.1186/s12985-016-0664-6) 

      Al-Qahtani, Ahmed A.; Alabsi, Enas S.; AbuOdeh, Raed; Thalib, Lukman; El Zowalaty, Mohamed E.; ... more authors ( BioMed Central Ltd. , 2017 , Other)
      Following publication of this article [1] it has come to our attention that Dr. Mohamed El Zowalaty should have been listed as a contributing author having been involved in the data entry, figure construction, writing and ...

    • Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update. 

      Saleh, Alaaeldin; Kashir, Junaid; Thanassoulas, Angelos; Safieh-Garabedian, Bared; Lai, F Anthony; ... more authors ( Frontiers Media , 2020 , Article Review)
      Sperm-specific phospholipase C zeta (PLCζ) is widely considered to be the physiological stimulus responsible for generating calcium (Ca) oscillations that induce egg activation and early embryonic development during mammalian ...

    • Estimating protection afforded by prior infection in preventing reinfection: Applying the test-negative study design. 

      Ayoub, Houssein H; Tomy, Milan; Chemaitelly, Hiam; Altarawneh, Heba N; Coyle, Peter; ... more authors ( Oxford University Press , 2023 , Article)
      The COVID-19 pandemic has highlighted the need to use infection testing databases to rapidly estimate effectiveness of prior infection in preventing reinfection ($P{E}_S$) by novel SARS-CoV-2 variants. Mathematical modeling ...