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السجلات المعروضة 1288 -- 1307 من 1584
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RNA splicing: a dual-edged sword for hepatocellular carcinoma
( Springer , 2022 , Article Review)RNA splicing is the fundamental process that brings diversity at the transcriptome and proteome levels. The spliceosome complex regulates minor and major processes of RNA splicing. Aberrant regulation is often associated ... -
The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy- Progress and Novel Therapeutic Opportunities
( Wiley , 2016 , Article)Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant genetic cardiovascular disorder marked by genetic and phenotypic heterogeneity. Mutations in the gene encodes the cardiac myosin-binding protein C, cMYBPC3 ... -
The role of community pharmacists in depression management: a survey of attitudes, practices and perceived barriers
( Springer , 2021 , Article)Background Community pharmacists play a significant role in depression care. Depression is a health priority in national health strategies around the world, including in Qatar. Objective To describe current practices, ... -
The Role of Copper Intake in the Development and Management of Type 2 Diabetes: A Systematic Review
( MDPI , 2023 , Article Review)Diabetes mellitus is a worldwide public health issue with numerous complications. Several risk factors are associated with diabetes, mainly due to patients following an unhealthy lifestyle. Copper is a crucial trace element, ... -
The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer.
( MDPI , 2019 , Article)Colorectal cancer (CRC) is one of the most common cancers worldwide, with high morbidity and mortality rates. A number of factors including modulation of the tumor microenvironment, high metastatic capability, and resistance ... -
The role of genetic and epigenetic GNAS alterations in the development of early-onset obesity
( Elsevier , 2023 , Article)BackgroundGNAS (guanine nucleotide-binding protein, alpha stimulating) is an imprinted gene that encodes Gsα, the α subunit of the heterotrimeric stimulatory G protein. This subunit mediates the signalling of a diverse ... -
The role of human metapneumovirus in pediatric respiratory tract infection in Qatar
( Future Medicine Ltd , 2010 , Article)The human metapneumovirus (hMPV) has been recently discovered as an etiological agent of acute respiratory infections in infants and children, with similar clinical symptoms to those caused by respiratory syncytial virus. ... -
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
( BMC , 2020 , Article Review)Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ... -
Role of nutrition in oral and pharyngeal cancers: From etiology to prevention
( Springer, Cham , 2017 , Book chapter)Oral and pharyngeal cancers (OPC) are highly prevalent tumors and rank as the sixth most common neoplasms. Some dietary factors have been linked to increased risk of OPC such as consumption of red meats and saturated fats, ... -
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
( Springer , 2023 , Article Review)Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ... -
The role of polymorphisms in vitamin d-related genes in response to vitamin d supplementation
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide ... -
The Role of Systemic Filtrating Organs in Aging and Their Potential in Rejuvenation Strategies
( MDPI , 2022 , Article Review)Advances in aging studies brought about by heterochronic parabiosis suggest that aging might be a reversable process that is affected by changes in the systemic milieu of organs and cells. Given the broadness of such a ... -
Role of the kinetic chain in shoulder rehabilitation: Does incorporating the trunk and lower limb into shoulder exercise regimes influence shoulder muscle recruitment patterns? Systematic review of electromyography studies
( BMJ Publishing Group , 2020 , Article Review)Objective To investigate the influence of trunk and lower limb motion on electromyography (EMG) muscle activity and recruitment patterns around the shoulder. Design Systematic review. Data sources MEDLINE, CINAHL, PEDro, ... -
The Role of Web-Based Adaptive Choice-Based Conjoint Analysis Technology in Eliciting Patients’ Preferences for Osteoarthritis Treatment
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Objective: To assess the feasibility of using adaptive choice-based conjoint (ACBC) analysis to elicit patients’ preferences for pharmacological treatment of osteoarthritis (OA), patients’ satisfaction with completing the ... -
Rotator cuff related shoulder pain. Describing home exercise adherence and the use of behavior change interventions to promote home exercise adherence: a systematic review of randomized controlled trials
( Elsevier , 2021 , Article)Background: A home exercise program (HEP) is integral in the management of rotator cuff related shoulder pain (RCRSP). There are many methods of measuring HEP adherence and many possible interventions to promote HEP ... -
Rotator cuff-related shoulder pain: Does the type of exercise influence the outcomes? Protocol of a randomised controlled trial
( BMJ Publishing Group , 2020 , Article)Introduction Lifetime prevalence of shoulder pain is 70%, and approximately 50% of people with shoulder pain will experience pain for more than a year. Rotator cuff-related shoulder pain (RCRSP) is the most common shoulder ... -
RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
( Public Library of Science (PLoS) , 2016 , Article)Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ... -
Safety
( Prentice Hall , 2011 , Book chapter)Contents: Introduction to diagnostic microbiology. Development of diagnostic microbiology ; Taxonomy and classification ; The bacterial cell ; The host's encounter with microbes ; Safety --Routine specimen processing. ... -
Safety profile comparison of chimeric live attenuated and Vero cell-derived inactivated Japanese encephalitis vaccines through an active surveillance system in Australia
( Taylor and Francis , 2022 , Article)Limited information is available about post-marketing safety of Japanese encephalitis (JE) vaccines. Using data from SmartVax, an active surveillance system for monitoring vaccine safety, adverse events following immunizations ... -
“Safe” Chitosan Zinc Oxide Nanocomposite Has Minimal Organ-Specific Toxicity on Early Stages of Zebrafish Development
( American Chemical Society , 2019 , Article)Marine biofouling is considered one of the most challenging issues affecting maritime industries worldwide. In this regard, traditional biocides, being used to combat biofouling, have high toxicity toward the aquatic system. ...