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AuthorBawadi, Hiba
AuthorKatkhouda, Rami
AuthorAl-Haifi, Ahmad
AuthorTayyem, Reema
AuthorElkhoury, Cosette Fakih
AuthorJamal, Zeina
Available date2016-10-09T10:48:05Z
Publication Date2016
Publication Namefood & nutritionen_US
Identifierhttp://dx.doi.org/10.3402/fnr.v60.29904
CitationFood & Nutrition Research 2016, 60: 29904
ISSN0304-8942
URIhttp://www.foodandnutritionresearch.net/index.php/fnr/article/view/29904
URIhttp://hdl.handle.net/10576/4845
AbstractBACKGROUND: Recently growing evidence indicates that obesity and diabetes are states of inflammation associated with elevated circulation of inflammatory mediators. Excess adiposity and oxidative stress, induced by feeding, may also lead to a state of low-grade inflammation. OBJECTIVE: This study aimed at investigating energy balance and distribution in relation to low-grade inflammation among patients with type 2 diabetes. DESIGN: A cross-sectional study included 198 male and female patients with type 2 diabetes. Patients' weight, height, waist circumference, total body fat and truncal fat percent, energy, and macronutrient intake were measured. Venous blood specimens were collected, and levels of HbA1c and serum levels of high-sensitivity C-reactive protein (hs-CRP) were determined. RESULTS: After adjusting for covariates (body mass index, total body fat, and truncal fat), energy balance was positively correlated with hs-CRP and HbA1c. A positive energy balance was also associated with increased waist circumference and truncal fat percent (p<0.05). Total energy intake, percent energy from fat (p=0.04), and percent energy from proteins (p=0.03), but not percent energy from carbohydrates (p=0.12), were also correlated with higher hs-CRP levels among poorly glycemic-controlled patients. CONCLUSION: Positive energy balance is associated with elevations in hs-CRP. Increased energy intake and increased percentages of energy from fat and protein are associated with elevated hs-CRP among patients with poor glycemic control.
SponsorJordan University of science and technology
Languageen
PublisherCo-Action Publishing
SubjectHbA1c
Subjectenergy balance
Subjecths-CRP
Subjecttype 2 diabetes
TitleEnergy balance and macronutrient distribution in relation to C-reactive protein and HbA1c levels among patients with type 2 diabetes
TypeArticle
Volume Number60


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