Browsing Medicine Research by Author "Benter, Ibrahim F."
Now showing items 1-4 of 4
-
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma
El-Hashim, Ahmed Z.; Khajah, Maitham A.; Babyson, Rhema S.; Renno, Waleed M.; Ezeamuzie, Charles I.; Benter, Ibrahim F.; Akhtar, Saghir... more authors ... less authors ( Public Library of Science , 2019 , Article)The angiotensin-(1–7) [Ang-(1–7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. ... -
Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma.
El-Hashim, Ahmed Z; Khajah, Maitham A; Babyson, Rhema S; Renno, Waleed M; Ezeamuzie, Charles I; Benter, Ibrahim F; Akhtar, Saghir... more authors ... less authors ( PLoS ONE , 2019 , Article)The angiotensin-(1-7) [Ang-(1-7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. ... -
Chronic administration of nano-sized PAMAM dendrimers in vivo inhibits EGFR-ERK1/2-ROCK signaling pathway and attenuates diabetes-induced vascular remodeling and dysfunction.
Akhtar, Saghir; Chandrasekhar, Bindu; Yousif, Mariam Hm; Renno, Waleed; Benter, Ibrahim F; El-Hashim, Ahmed Z... more authors ... less authors ( Elsevier , 2019 , Article)We investigated whether chronic administration of nano-sized polyamidoamine (PAMAM) dendrimers can have beneficial effects on diabetes-induced vascular dysfunction by inhibiting the epidermal growth factor receptor ... -
Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart
Akhtar, Saghir; Babiker, Fawzi; Akhtar, Usman A.; Benter, Ibrahim F. ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation ...