Browsing Medicine Research by Author "El-Achkar, Ghewa A."
Now showing items 1-2 of 2
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The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model
Firas, Kobeissy; Mallah, Khalil; Zibara, Kazem; Dakroub, Fatima; Dalloul, Zeinab; Nasser, Mohammad; Nasrallah, Leila; Mallah, Zahraa; El-Achkar, Ghewa A.; Ramadan, Naify; Mohamed, Wael; Mondello, Stefania; Darwish, Hala; Hamade, Eva; Habib, Aida... more authors ... less authors ( Elsevier , 2022 , Article)Traumatic Brain Injury (TBI) is one of the leading causes of death and disability worldwide. Aspirin (ASA) and clopidogrel (CLOP) are antiplatelet agents that inhibit platelet aggregation. They are implicated in worsening ... -
Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris
Jaffa, Aneese A.; Jaffa, Miran A.; Moussa, Mayssam; Ahmed, Ibrahim A.; Karam, Mia; Aldeen, Kawthar Sharaf; Al Sayegh, Rola; El-Achkar, Ghewa A.; Nasrallah, Leila; Yehya, Yara; Habib, Aida; Ziyadeh, Fuad N.; Eid, Ali H.; Kobeissy, Firas H.... more authors ... less authors ( Frontiers Media , 2021 , Article)Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, ...