Browsing Medicine Research by Subject "meta-analysis"
Now showing items 1-20 of 25
-
Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives
( Wiley Open Access , 2020 , Article)© 2020 The Authors. Health Science Reports published by Wiley Periodicals LLC. Meta-analyses have been increasingly used to synthesize proportions (eg, disease prevalence) from multiple studies in recent years. Arcsine-based ... -
Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A metaanalysis
( Public Library of Science , 2022 , Article)Introduction Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a ... -
Bias Assessment in Outcomes Research: The Role of Relative Versus Absolute Approaches
(2021 , Article)ObjectivesBias assessment tools vary in content and detail, and the method used for assessment may produce different assessment results in a study if not carefully considered. Therefore, taking an approach to the assessment ... -
Comment on a review of methods to assess publication and other reporting biases in meta-analysis
( John Wiley and Sons Ltd , 2022 , Article)We read with interest the well-written review on the assessment of publication and other reporting biases in meta-analysis by Page et al.1 in which both funnel plots and tests for its asymmetry were described. The decision ... -
Does the Sex of the Firstborn Child Affect the Breast Cancer Risk and Survival: A Systematic Review and Meta-analysis of Over 1 Million Cases
( Galenos Yayinevi , 2022 , Article)Background: Reports on the risk and prognosis of breast cancer in relation to the sex of a child have been conflicting. Since medical sciences play an important role in informing sociocultural understandings of health and ... -
Effectiveness of Different Topical Treatments in the Healing of Pressure Injuries: A Network Meta-analysis.
( Elsevier , 2018 , Article)Pressure injuries (PIs) are one of the most common types of complex wounds and impose a huge economic burden on the healthcare system and the patients. A plethora of topical treatments is widely available for PI treatment, ... -
Effectiveness of Market-Level Biosecurity at Reducing Exposure of Poultry and Humans to Avian Influenza: A Systematic Review and Meta-Analysis.
( Oxford University Press , 2018 , Article)In this study, we aimed to identify the effect of market-level risk factors on avian influenza (AI) infection in poultry and humans and generate evidence that will inform AI prevention and control programs at live bird ... -
Empirical Comparisons of 12 Meta-analysis Methods for Synthesizing Proportions of Binary Outcomes
( Springer , 2021 , Article)Background: Meta-analysis is increasingly used to synthesize proportions (e.g., disease prevalence). It can be implemented with widely used two-step methods or one-step methods, such as generalized linear mixed models ... -
Examining how meta-analytic methods perform
( Wiley , 2022 , Other)I read with interest the paper by Bramley et al.1 that concluded (regarding error estimation) that the IVhet method often outperforms the Henmi-copas (HC) method with fewer than 10 studies. They also concluded that the ... -
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
( Taylor & Francis , 2019 , Article)Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize that the ... -
Meta-analysis of intracavitary electrocardiogram guidance for peripherally inserted central catheter placement
( SAGE Publications Ltd , 2019 , Article Review)Background: Recently, intracavitary electrocardiogram technology has been applied to peripherally inserted central catheter placement and demonstrates many potential advantages. However, the tip positioning accuracy of ... -
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
( Elsevier , 2021 , Article)The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ... -
Methodological assessment of systematic reviews and meta-analyses on COVID-19: A meta-epidemiological study
( Wiley , 2021 , Article)Rationale, aims, and objectives: COVID-19 has caused an ongoing public health crisis. Many systematic reviews and meta-analyses have been performed to synthesize evidence for better understanding this new disease. However, ... -
Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
( Elsevier , 2021 , Article)An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three ... -
Methodological quality assessment should move beyond design specificity.
( Lippincott, Williams & Wilkins , 2023 , Article)This study aimed to assess the utility of a unified tool (MASTER) for bias assessment against design-specific tools in terms of content and coverage. Each of the safeguards in the design-specific tools was compared and ... -
A new improved graphical and quantitative method for detecting bias in meta-analysis.
( Lippincott, Williams & Wilkins , 2018 , Article)Detection of publication and related biases remains suboptimal and threatens the validity and interpretation of meta-analytical findings. When bias is present, it usually differentially affects small and large studies ... -
A new method for synthesizing test accuracy data outperformed the bivariate method
( Elsevier , 2020 , Article)This paper outlines the development of a new method (split component synthesis; SCS) for meta-analysis of diagnostic accuracy studies and assesses its performance against the commonly used bivariate random effects model. ... -
Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
( Frontiers Media S.A. , 2023 , Article)Background and objectives: Polypharmacy and chronic kidney disease (CKD) are becoming increasingly common due to an ageing population and the rise of multimorbidity. In line with the therapeutic guidelines, managing CKD ... -
A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies
( Elsevier , 2021 , Article)ObjectiveIn evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare practice. We ... -
Rendering the Doi plot properly in meta-analysis.
( International Journal of Evidence-Based Healthcare , 2018 , Other)NA