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An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study
(
Springer Nature
, 2023 , Article)
Objectives: To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways. Methods: We analyzed a cohort of 39 ...
Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic ...
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
(
Springer Nature
, 2023 , Article)
There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ...
Characteristic MicroRNAs Linked to Dysregulated Metabolic Pathways in Qatari Adult Subjects With Obesity and Metabolic Syndrome.
(
Frontiers
, 2022 , Article)
Obesity-associated dysglycemia is associated with metabolic disorders. MicroRNAs (miRNAs) are known regulators of metabolic homeostasis. We aimed to assess the relationship of circulating miRNAs with clinical features in ...