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Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells
(
MDPI
, 2022 , Article)
Chemokine receptor CCR7 is implicated in the metastasis of breast cancer to the lymph
nodes. Chemokine function is dependent upon their binding to both cell-surface heparan sulphate
(HS) and to their specific receptors; ...
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
(
MDPI
, 2015 , Article Review)
Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ...
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review.
(
Oxford University Press
, 2023 , Article Review)
Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ...