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Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation
(
Taylor & Francis
, 2019 , Article)
Ropinirole hydrochloride (RH) is an anti-Parkinson drug with relativity low oral bioavailability owing to its extensive hepatic first pass metabolism. Spray-dried mucoadhesive alginate microspheres of RH were developed and ...
Introduction to nanotechnology
(
Elsevier
, 2019 , Book chapter)
Nanotechnology describes the science and technology related to the control and manipulation of matter and devices on a scale less than 100 nm and involves fields such as applied physics, materials science, chemistry, ...
Guiding Factors and Surface Modification Strategies for Biomaterials in Pharmaceutical Product Development
(
Elsevier
, 2019 , Book chapter)
With the technological advent in the field of drug delivery and medicines, biomaterials become important owing to their properties such as biocompatibility, functionality, and bioactive and bioinert nature. However, the ...
Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer.
(
Elsevier
, 2019 , Article)
The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs). Elevated activity of cytochrome P4501A1 (CYP1A1) plays an important role in the metabolic ...