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Evaluating the effects of sodium glucose co-transporter -2 inhibitors from a renin–angiotensin–aldosterone system perspective in patients infected with COVID-19: contextualizing findings from the dapagliflozin in respiratory failure in patients with COVID-19 study
(
Springer
, 2022 , Article Review)
Numerous studies demonstrate parallels between CVD, type 2 diabetes mellitus (T2DM) and COVID-19 pathology, which accentuate pre-existing complications in patients infected with COVID-19 and potentially exacerbate the infection ...
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
(
Springer
, 2022 , Article)
Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ...
Identifying the core concepts of pharmacology education: A global initiative
(
Wiley-Blackwell
, 2022 , Article)
Background and Purpose: In recent decades, a focus on the most critical and fundamental concepts has proven highly advantageous to students and educators in many science disciplines. Pharmacology, unlike microbiology, ...
Developing Leadership Skills in Pharmacy Education
(
Springer
, 2022 , Other)
Leadership could refer to holding official leadership positions or advocating for patients and the profession. Different pharmacy organizations recommend the inclusion of leadership development in pharmacy education and ...
Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer
(
Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
, 2023 , Article)
Genomic and proteomic mutation analysis is the standard of care for selecting candidates for therapies with tyrosine kinase inhibitors against the human epidermal growth factor receptor (EGFR TKI therapies) and further ...
The design and implementation of an undergraduate health professional degree elective course on scientific writing, peer assessment, and critical appraisal
(
Elsevier
, 2022 , Other)
Background and purpose: Strong writing skills are critical to the pharmacy profession. This paper describes the design, delivery, and impact of a course intended to develop pharmacy students' scientific writing, peer ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...
Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Metabolic changes are an important component of tumor cell progression. Tumor cells adapt to environmental stresses via changes to carbohydrate and lipid metabolism. Autophagy, a physiological process in mammalian cells ...
Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
(
Elsevier
, 2020 , Article)
Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ...
Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Metabolic changes are an important component of tumor cell progression. Tumor cells adapt to environmental stresses via changes to carbohydrate and lipid metabolism. Autophagy, a physiological process in mammalian cells ...